D. Jin and S. Lin (Eds.): Advances in FCCS, Vol. 2, AISC 160, pp. 561–565.
Model with Nonlinear Incidence Rate
Xiuxiang Yang1, Feng Li1, and Yuanji Cheng2 1
Department of Mathematics, Weinan Normal University, Weinan 714000 Shaanxi, China
2
School of Technology Malmo University, SE-205 06 Malmo, Sweden yangxiuxiang2000@yahoo.com.cn, lifeng5849@163.com,
yuanji.cheng@mah.se
Abstract. An SIQ epidemic model with isolation and nonlinear incidence rate is studied. We have obtained a threshold value
R
and shown that there is only a disease free equilibrium point whenR
<
1
, and there is also an endemic equilibrium point ifR
>
1
. With the help of Liapunov function, we have shown that disease free- and endemic equilibrium point is globally stable.Keywords: SIQ model, Isolation, nonlinear infectious rate, threshold, equilibrium point, global stability.
1 Introduction
In this paper, we shall as well exploit the Lyapunov direct method to study the global stability analysis on the dynamics of an SIQ model with nonlinear incidence rate. Assuming that the population has a very short immunity period, which is negligible, and whence there is a class of recovered and the models being studied here are of SIQ type. Assume that the total population is divided into: S = S(t) susceptible, I(t) infected, Q(t) isolated and R(t)recovered classes at time t. Let A be the constant migration rate of the population, and d be natural death rate of each kind,
α
1 andα
2 be the infected death rate of infectious and isolated classes respectively, andδ
be the transition rate from infected to isolated classes,r
,ε
be immunity’s lose rate of infected respectively isolated classes. We assume that the constantsd
,δ
,A
are positive, andr
,ε
,δ
,α
1,α
2 are nonnegative . Thus we consider the' ' 1 ' 2
( )
1
( )
(
)
1
( )
(
)
IS
S t
A
dS
rI
Q
mI
IS
I t
r
d
I
mI
Q t
I
d
Q
β
ε
β
δ
α
δ
ε
α
⎧⎪
= −
−
+ +
⎪⎪
+
⎪⎪
⎪⎪
=
− + + +
⎨
+
⎪⎪
⎪
=
− + +
⎪⎪
⎪⎪⎩
(1)
we see that N satisfies:
N t
'( )
= −
A
dN
−
α
1I
−
α
2Q
≤ −
A
dN
,thus
0
( )
dtA
(1
dt)
N t
N e
e
d
− −≤
+
−
(2) It follows from the above estimates that the solutions of initial value problem for system (1) exist on
[0,
+∞
)
,is invariant subset of (1).
2 Local Stability of Equilibrium
To find the equilibrium of system (1), we get the equilibrium
P
0(
A
d
, 0, 0)
and
P S I Q
1( , ,
1 1 1)
, let’s define the threshold number for (1)1 1
(
)
d r
d
R
A
δ
α
β
+ + +
=
,Then we have thatP
1 is in3
R
+ if and only if R < . 1 1 Here 1 1 1(
)
(1
)
r
d
S
δ
α
mI
β
+ + +
=
+
,
1 2 2 I Q d δ ε α = + +,
1 1 2 1 1 2(
)
(
)
(
)
(
)
A
d r
d
I
d
md r
d
d
d
β
δ α
δ
α
δ α
β
α
ε
α
−
+ + +
=
+
+ + +
+
+
+
+ +
Theorem 1. For the system (1), the infection-free equilibrium point
P
0 is locally asymptotically stable if R > , If 1 1 R < , then the endemic equilibrium point 1 1P
1 islocally asymptotically stable and
P
0 becomes unstable.Proof. First we consider the system (1) and the infectious free equilibrium
P
0, TheJacobian matrix
J P
( )
0 ,Which has eigenvalues:1
(
d
)
0
λ
= − + <
ε
, 2A
(
r
d
1)
d
β
λ
=
− + + +
δ
α
,λ
3= − + +
(
ε
d
α
2)
<
0
, When R < , then 1 1λ
2 is also negative, and henceP
0 is locally stable.In the
P
1,β
S
2= + + +
(
r
d
δ α
1)(1
+
mI
2)
. Letd
i= +
d
α
i,
i
=
1, 2
According to
J P
( )
1 , the associated characteristic equation is3 2
1 2 3
0
b
b
b
1 2
(1
2)
2(
1)
(
2)(1
2)
0
b
=
β
I
+
d
+
mI
+
mI r
+ +
δ
d
+ +
ε
d
+
mI
>
2 2 2 2 1 2 2 2 2 2 1 2 2 2 1 2(
)
(
)
(
)(
)(1
)
(
)(
)(1
)
(
)
0
b
I
d
dmI mI r
d
I
d
dmI
d
mI
mI r
d
d
mI
I
d
rmI
β
δ
β
ε
δ
ε
β
δ
=
+ +
+ +
+
+ +
+
+
+
+ +
+
+
+
+ −
>
3 2 2 2 1 2 2 2 2 2 2 1 2 2(
)(1
)(
)(
)
((
)(1
)(
)
(1
) )
0
b
mI
d
mI
r
d
I
d
dmI
I
d
mI
d
rmI
mI
ε
δ
β
β
ε
δ
δε
=
+
+
+ +
+ +
+
+
+
+ −
−
+
>
To verify the Hurwitz condition b b1 2−b3> 0 , we first rewrite:
1 10 11 2
b
=
c
+
c mI
, 2 2 20 21 2 22(
2)
b
=
c
+
c mI
+
c
mI
,
2 3 3 30 31 2 32(
2)
33(
2)
b
=
c
+
c mI
+
c
mI
+
c
mI
,
Wherec
10= + +
d
ε
d
2+
β
I
2 ,c
11= + + +
d
r
ε
d
2+ +
δ
d
1 ,c
20=
d
(
ε
+
d
2)
+ +
(
ε
d
2+ +
δ
d
1)
β
I
2, 21(
1)(
2)
(
2)(
2 1)
c
=
rd
+ + +
r
δ
d
ε
+
d
+
d
+
β
I
ε
+
d
+ +
δ
d
,
22(
1)(
2)
(
2 1)
c
= + +
r
δ
d
ε
+
d
+
d r
+ +
ε
d
+ +
δ
d
,
30(
1 2 1 2)
2c
=
ε
d
+
δ
d
+
d d
β
I
,
31(
1)(
2)
2(
1 2 1 2)
2c
=
d r
+ +
δ
d
ε
+
d
+
ε
d
+
δ
d
+
d d
β
I
,
322 (
1)(
2)
(
1 2 1 2)
2c
=
d r
+ +
δ
d
ε
+
d
+
ε
d
+
δ
d
+
d d
β
I
,
33(
1)(
2)
c
=
d r
+ +
δ
d
ε
+
d
.
Then get 1 2 3 10 20 30(
10 22 11 20 31)
2b b
− =
b
c c
−
c
+
c c
+
c c
−
c
mI
+
2 10 22 11 21 32 2(
c c
+
c c
−
c
)(
mI
)
+
(
c c
11 22−
c
33)(
mI
2)
3 0:
10 20 300,
1:
10 22 11 20 310
C
=
c c
−
c
>
C
=
c c
+
c c
−
c
>
,
2:
10 22 11 21 320,
C
=
c c
+
c c
−
c
>
C
3=
:
c c
11 22−
c
33> ,
0
So 1P
is locally asymptotically stable.3 Global Stability of Equilibrium
Theorem 2. For the system (1), If
R >
11
, then the disease free equilibriumP
0 of (2) is globally asymptotically stable; whenR <
11
, thenP
0 is unstable, and the endemic equilibrium pointP
is globally asymptotically stable.Proof. we can easily proof the disease free equilibrium
P
0 of (1) is globallyasymptotically stable same as theorem. Following discuss asymptotic stability of
P
1, we again change variableN
= + +
S
I
Q
1 2 ' 1 ' 2
'( )
( )
[ (
)
(
)(1
)]
1
( )
(
)
N t
A
dN
I
Q
I
I t
N
I
Q
r
d
mI
mI
Q t
I
d
Q
α
α
β
δ
α
δ
ε
α
⎧
= −
−
−
⎪⎪
⎪⎪
⎪
=
− −
− + + +
+
⎨⎪
+
⎪⎪
⎪
=
− + +
⎪⎩
1,
1,
1x
= −
N
N y
= −
I
I z
= −
Q Q
, then we deduce1 2 2 2 2 2
'( )
'( )
(
(
(
))
)
1
(
)
'( )
(
)
x t
dx
y
z
y
I
y t
x
m r
d
y
z
m y
I
z t
y
d
z
α
α
β
β
δ α
β
δ
ε
α
⎧
= − −
−
⎪
+
⎪
=
−
+
+ + +
−
⎨
+
+
⎪
⎪
=
− + +
⎩
(3)
We have used the relation
(
r
+ + +
δ
d
α
1)(1
+
mI
2)
=
β
S
2=
β
(
N
2− −
I
2Q
2)
Choose the Liapunov function 2 2 2 2 3 1 2 2 2 ( ) ( ln(1 ) ) 2 2 2 2 z x y my x z V y I I ω ω ω − = + − + + + + 1 1 2 2 2 (3)
(
)
(
(
(
))
)
dV
x
dx
y
z
y
x
m r
d
y
z
dt
=
ω
− −
α
−
α
+
ω
β
−
β
+
+ + +
δ α
−
β
+
ω δ
3z
(
y
− + +
(
ε
d
α
2) )
z
+ −
(
x
z
)(
− − +
dx
(
δ α
1)
y
+ +
(
ε
d z
) )
2 2 1 2 1 1 1 2 1 2 2 (1 ) ( ) ( 2 ) ( ( )) d ω x ω β ω α α δ xy ε d α ω xz ω β m r d δ α y = − + + − − − + + − − + + + +
+(α1+ +δ ω δ3 −ω β2 )y z−(ε+ d +(ε+ d +α ω2) 3)z2 If we choose
ω ω ω >
1,
2,
30
1 1 1 1 1 1 2 3 2 ( ) (ε 2 )d , ω α α δ , ω α ω = + α ω = + + β ω = δ,
2 2 2 1 2 2 2 3 (3) (1 ) ( ( )) ( ( ) ) dV d x m r d y d d z dt = − +ω −ω β+ + + +δ α − + +ε ε+ +α ωWhich is clearly negative definite. Hence,
P S I Q
1( , ,
1 1 1)
is globally asymptoticallyReferences
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