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Historia febris intermittentis petechialis, qvam venia ... med. ord. Ups. præside Joh. Gust. Acrel ... pro gradu doctoris publice ventilandam sistit Joh. Sigfr. Schedvin, Dalecarlus. In audit. Gust. maj. d. XXVII Apr. MDCCXCIII. Horis a. et p. meridiem so

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H I S T O R I A

FEBRIS INTERMITTENTIS

P E T E C H I A L I S ,

&

Q V A M

F E S I A EXPER1EN TISS. MED. ORD. UPS.

P R Æ S I D E

G UST.

M. D. M E D . T H F O R G T . E T PRACT. P R O F . REG. E T O R D . REG. ACAD. S C I E N T . HOLM. A T Q U E S O C . REG. SC IEN T.

UPS. MEMBRO, C E T .

P R O G R A D U D O C T O R I S

PUBLICE VENTILANDAM SISTIT

A O H . S I G F R . S C H E D F I N ,

D A L E C A R L U S .

IN AUDITORIO GUST. MAJ. D. X X V II APR. MDCCXCIII.

HORIS At KT P* M E R I D I E M SODITTS.

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applicatis-i cafti ope ratiocinii, legitime dedu&a fu n t, quan-

quam per fe in fenfus non cadunt, non prtfefto minorem fi­

dem merentur.

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H I S T O R I A

FEBRIS I N T E R M I T T E N T I S

P E T E C H I A L I S .

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j F Ï L i l l o r i a m M o r b i , ut o p i n a m u r , r a r i o r i s , et cujus apud A u d l o r e s , five a n t i q v i o r e s live r e c e n t i o r e s c o n f u l u e r i s , p e r p a u c a e x i l a n t e x e m p l a , d u m b e n i g n i o r i t u o , Bene­ v o l e L e c t o r , j u d i c io f u b j i c i m u s , id n o n ita i n t e l l e £ t u m v o l u m u s , ac li in p a r t e s i l l o r u m t r a n f i r e m u s , q u i , quafi m a l o q u o d a m fæculi g e n i o d u £ l i , e x f i ng u l ar i cafu r e g u ­ las g e n e ra le s h a u r i u n t arque e x t o r q u e n t ; in e o e n i m p o ­ tius n o l l r a v e r f a b i r u r o p e r a , ut M e d i c o s a t t e n t o s f a c i a m u s c i r c a p h a e n o m e n a q u a e d a m , quae, licet r a r i u s o c c u r r a n t ) t a m e n ad i n d a g a n d a m m o r b o r u m i n d o l e m conferre pos- fu n t, q u a m ut o p i n i o n e s n o l t r a s t a m q u a m certas atque o m n i e x p e r i e n t i a Habilitas v e n d i r e m u s . P e t e c h i a r u r a in f e b r i b u s o r t u m praeviae f a n g v i n i s , p u t r e d i n i v i c i n i , disfo- l u t i o n i , ad h o c usque t e m p u s t r i b u e r e Pra£t icis m o s fuit, A n v e r o m u t a t a e j u s m o d i f a n g v i n i s i n d o l e s causfa prim a­ ri a fit vel f e c u n d a r i a , a vitalitate fcilicet Fibrarum prius i m m i n u t a , o r i u n d a , adhuc in d u b i u m vocare licet: de his faltim in utramque pantem difputatur. A t II cafu p r o ­

b a t u m fuerit, non folum Petechias, verura etiam veficulas

f a n g v i n e genuino repletas, easqut numerofisfimas, totam

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q u e c o r p o r i s f u p e r f i c i e m o c c u p a n t e s , i n t e r in i ti a febris eu- j u s d a m o r t a s effe; t u n c fatisne validæ a d f u n t r a t i o n e s , ft n o n p r o r f u s n e g a n d i , t a m e n v e h e m e n t e r d u b i t a n d i , q v i n

i m m u t a t u s hicce f a n g v i n i s f l a t u s , q u e m v u l g o ca us f am c r e d u n t , p o t i u s , ut q u i d e m fæpisflme effe v i d e t u r , e f f e ­ ctus diminutae vitalitatis f o l i d o r u m h a b e n d u s f i t ? Quae­

ri a m e x his elici poffurit a r g u m e n t a fi i l l a a d h u c e r e effent ad f i r m a n d a m , d o & r i n a m ab H o f f m a n n o p r i m o c o n d i ­

t a m , d e i n v e r o n e g l e & a m , fed a C u l l e n i o d e n o v o as“ fumfcam, er jam t e m p o r i s quafi u n o o r e c o n f e f f a m atque r e c e p t a m , de fibra v i v a et infigni c o g n i t i o n i s ejus d e i n in P a t h o l o g i a v er i t at e . C a f u m t a n t u m m o d o e n a r r a m u s , a d ­

ditis, q u a s res ipfa p r æ b u i t , O b f e r v a t i o n i b u s ; et d u m de hi s T e , LeCtor B e n e v o l e , j u d i c e m l u b e n t e s c o n f f i t u i m u s , f a v e n t i o r e r o firnul abs T e e x p e t i m u s c o n a m i n i s i n t e r p r e -sationem.

Cajus.

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Duella n o v e m a n n o s nata, exili a t q u e t e n e r i o r i c o r p o ­ris h a b i t u , f e m p e r t a m e n b o n a v a l e t u d i n e u f a , t e m ­ p o r e v e r n a l i f e b r e t e r t i a n a i n f a n t u m ( d l t a n

dicunt noßt fi­

tes')

c o r r i p i e b a t u r , h a n c a u r e m i n e u n r e c a i i d i o n anrii tem- peftat e facile p r o f l i g a b a n t diæta o p p o r t u n a et C o i rex p e -

ruvianus, i d q u e a b s q u e o m n i c o n f e q v e n t e i n c o m m o d o , a d e o ut p e r t o t a m æ fl a t e m vel f e r e fex i n t e g r o s m e n f e s o p t i m e val eret . M e n f e N o v e m b r i s e j u s d e m a n n i , l a n g v i d a , t n f t i s , cibumque faftidiens adparuit, q u o fub flatu fex c i r ­

(5)

c i t e r dies praeterlapfi funr. V e h e m e n t e m ac i n o p i n a r u m i m p e t u m h o r r o r u m , caloris, a l i o r u m q u e , quce f e br es comi - r a n t u r ; f y m p t o m a t u m p e r f e n t i i t p o f t e r o d i e f u b f e q u e b a t u r va- r i e g a t u s f a c i e i , colli arque p e c o r i s col or, e o d e m q u e die ve* f p e r a f c e n t e maculis m a g i s c o nf pi c u i s , p a r v i s , r o t u n d i s , laete r u b e n t i b u s et m a g n i t u d i n e i£tus p u l i c u m quali c o n f p e r f a v i ­ d e b a t u r Æ g r a ; febri s lenis e r a t er o b a m b u l a r e v a l u i t ; at v e f p e r t i n o t e m p o r e levi s e x a c e r b a t i o . O b t a r d a m a l v u m L a x a n s fumfit. D i e i f : d a maculae n u m e r o au£læ t a m e n a b s q u e r u ­ b o r e cutis intermediae, h o d i e in m a n i b u s q u o q u e b r a ch i i s e t a r t u b u s i n f e r i o r i b u s fe m a n i f e f t a r u n t . C o l o r n u p e r e r u p t a r u m r u b e r , b e f t e r n a r u m v e r o p a u l o n i g r i o r fa&us. F e b r i s ut heri mitis. M i x t u r a falina u t e b a t u r .

-Hirt ia Di e febri s v e r f u s m e r i d i e m r e d i i t fine f r i g o r e p r æ g r e f f o notabili; c a l o r m o d i c u s , pul f us v e r o f r e q u e n s et c e l e r : V e f p e r t i n o t e m p o r e h a e m o r r h a g i a n a r i u m c o p i o f a et difficulter fi f l e n d a f u p e r v e n i t . I n vafe cito c oa gul a t us fuit fa n g vi s . P e r e c h i æ faciei d i l a t a t æ , f u b t e r p a l p e b r a s in m a g n a s fug i l l a t i o ne s c o e u n t e s , u b i q u e v e r o t a m in f a ­ c ie q u a m in t r u n c o , r o t u n d a m Tuam f o r m a m f e r v a n t e s , c o l o r e m i n d u e n t e s l i v i d u m , q u o a f p e c t u s Æ g r a e l u gubr is evafit. N o £ t e i t e r u m Epiftaxis far. c o p i o f a bis e ru p i t . M i x t . Salin, fumfit et v e f p e r a m v e r f u s C l y s m a .

I V :t a D i e , f e b r e m li f p e c t a v e r i s , me l ius valuit. Maculae plurimse faciei in v e f c u l a s elevatas m a g n i t u d i n e va r i ol a- r u m d i f c r e t a r u m a b i e r u n t ; acu p e r c u s f æ f a n g v i n e m n i g r u m , c r a s f u m e m i t t e b a n t . De nullo f e r e i n c o m m o d o , d e b i l i t a ­ r e m et d o l o r e m cutis p u n g e n t e m fi e x c e p e r i s , c o n q u e r e ­ b a t u r Æ g r a . S o m n o m i n u s v e r o t r a n q v i i l o m u l t u m in- dulfit. D i g c f t i v a m i t i o r a e x h i b i t a fuere-V ; t a D i e f ebr is v e h e m e n s c u m c a l o r e , pulfu c i t a t o , fiti u r e n t e l i n g v a q u e albo o b d u d t a m u c o ; E x a n t h e m a e t ­ i a m

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i a m in t r u n c o , c r u r i b u s p e d i b u s q u e c o p i o f u m r e p c r i e b a - t u r . V e f p e r a et f e q u e n t e no£te r u r f u s h æ m o r r h a g i a n a ­ r i u m i n c e r t æ q u a n t i t a t i s , n u n c v e r o f a n g v i s m i n u s e oa - gulabilis, c o l o r e fl or i di or i fuit. Pulfus v e f p e r a m v e r f u s d e bi l is et l a n g v o r au£tus.

V I : r a D i e f e b r i s q u i d e m d i m i n u t a , v e r u m cu t i s p a l ­ l e n s et m o r i e n t i u m f i m i l l i m a , c u m E c l i y m o i i b u s p a l p e ­ b r a r u m n i g r i s er veliculis f a n g v i n e i s lividis faciei a d f p e - £tu pesfime c o n c o r d a b a r . Q u o n i a m fub d e c u r f u f e b r i s t y ­ p u m tertianae b a u d d u b i t a n t e r o b f e r v a r e licuerat, e t f y m p r o - m a t i b u s reliquis ci t o atque v a l e n t e r o c c u r e n d u m erat, I n f u • f um for t ius C o r t . P e r u v . et A c i d u m V i t r i o l i t e n u e , S y r u p o C e r a f o r . e d u l c o r a t u m , p r æ f c r i b e b a n t u r . V I T : m a O i e , flatus Æ g r æ h e f t e r n o p e j o r . A cc es f l on i s i n c e p t i o o b d e f i c i e n t e m f r i g o r i s fenfiim i ncert a. H o r i s p o m e r i d i a n i s Epiflaxis r e d i t et f a n g v i s e n a r i b u s m a n a n s m a g i s attenuatus. U f u s Acid. V i t r . c o n t i n u a b a t u r .

V l I I : a D i e no£le p r æ t e r i t a , veficulæ f a n g v i n e æ dor* f u m , f e m o r a et c r u r a o b f i de n t e s ab i n c ub i t u r u p t æ , lc£ti l i n t e o l a f a n g v i n e m a c u l a r u n t ; Veficulis ex his q u æ in b r a c h i i s e r a n t acu a p e r t i s , f a n g v i s crasfus j a m q u e c o a g u ­ latus profiliebat. F e b r i s q u i d e m adfuit fed mitior. I n- fus. K i n k i n æ , Acid. V i t r . et v e r f u s n o b l e m C l y s m a K i - n a t u m p r o p i n a b a n t u r . A IXrna ad X I : a m D i e m Æ g r a debilis a d e o e r a t , ut v i x fe m o v e r e v a l e r e t ; pulfus p a r v u s et debil is v e f p e r e v e r o i n c i t a t i o r , m a t u t i n o t e m p o r e f u d o r et u r i n a h y p o * ftica c u m f e d i m e n t o r u b i c u n d a . C e t e r i s r e m e d i i s v i n o - fa c u m jufculis n u t r i e n t i b u s a d d i t a funt. X U : a Die p a u l l u m a l a c r i o r Æ g r a c i b u m a d p e t i i t : E* c h y m o f e s p a l p e b r a r u m d e c r e f c u n t , c o l o r e m q u e f l avefcen- t e m i n d u u n t ; P e t e c h i æ d i f p a r u e r u n t er veficulæ f a n g v i n e æ , e o d e m q u o cruftæ v a r i o l a r u m m o d o , c x f l c c a b a n t u r . M e ­ d i c a m e n t a eadem.

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A XV: a ad X V I I I : a m D i e m r e f anefcuir: cruftce e x t r e ­ m i t a t u m d e c i d e b a n t , C o r t i c e m t a m e n P e r u v i a n u m n i h i l o ­ m i n u s p e r a l i q u o d t e m p u s f u m f i t et p e r a n n u m fere in* t e g r u m o p t i m e valui t.

M e n f e S e p t e m b r i s a n n i f e q u e n t i s , p o f t q u a m p e r fepti- m a n a m vel ul t ra v a c i l l a v e r a t v a l e t u d o , febri s accesfio- n e m pafla e f t , i t e r u m q u e fo l it æ P e t e c h i æ f a c i e i , p a l p e ­ b r a r u m E c h y m o f e s et ve f i cul æ f a n g v i n e æ , in reliquas q u o q u e c o r p o r i s p a r t e s d i f p e r f a s , c o n f e f t i m a d p a r u e r e n ec defuit pe r n a r e s p r o f l u v i u m c r u e n t u m . V e r u m f e ­ b r i s c e t e r a q u e f y m p t o m a t a m i r u m q u a n t u m , fi fcilicet ea c u m a nt ea recenfitis c o m p a r a v e r i s , mitia f u e r e , et u n d e ­ c i m a ab i n g r e f l u die, C o r t i c e K i n k i n æ et Acid. V i t r . o p ­ p o r t u n e ad hi bi ti s c u r a b a t u r m o r b u s . , D i a r h e f e o s Sc or bu- ricæ vel q u i d e m levisfima f i gna t a m a nt e q u a m poft m o r ­ bos j a m d e f c r i p t o s , in Æ g r a p r o r f u s d e f u e r e . F e b r i b u s E x a n r h e m a t i c i s , V a r i o l æ 1. M o r b i l l i e x e m p l o fint, m i n i m e a d n u m e r a r i d e b e t , n a m a n n o p r o x i m o i n o c u l a t i o n e m Va- r i o l a r u m felici c u m fucceflu f u b i i t , et M o r b i 1 lis poft bi ­ e n n i u m laboravit. F e b r e m n o n c o n t a g i o f a m fuifle ex e o p a t e t , q u o d n e m o p l u r i u m i n f a n t u m un a c u m illa v i v e n ­ t i u m , nec p r i m a nec altera v i c e , m o r b o c o r r i p e r e n t u r . .

N u l l i p e r p r o v i n c i a m E p i d e r n i a g r a s f a b a t u r , q u æ ad i n ­ d a g a n d a m m o r b i i n d o l e m vel m i n i m u m m o m e n t u m ad- f e r r e p o t u i t , q u a p r o p t e r i l iu m i d i o f y n c r a f i æ Æ g r æ p l a n e a t q u e o m n i n o t r i b u e n d u m efle e x i f t i m a m u s (//)„

Co-( a ) I d i o f y n c r a f i a m h t i i c f i m i l e m o b f e t vftvit C l . J. D . R o g e r t : Vide: O b f . i t M o r b o mnculojb H j m o n b f i g i c o , iu A f t . R e g . Soc. M ed . Hafn, T o m » .

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-Corollaria.

I. F e b r e m , q u a m E x a n r h e m a ho c c o m i r e m h a ­ b u i t , I n t e r m i t t e n t i u m g e n e r i m e r i t o a d d e n d a m c r e d i m u s , q u u m accesfiones fatis m a n i f e f t o alternis d i e b u s Æ g r a m

a d g r e d i e b a n t u r . T e r t i a n a e praeterea c u m i Per echi i s f æp i us o b f e r v a t æ funt, et(i E p i d e m i æ nonnullae C o r t i c i P e r u - v i a n o o b t e m p e r a v e r i n t , aliae a u t e m illum v i x p o t u e r i n t

f e r r e

(JF)..

II. F e b r i s nof tr a has o b r a t i o n e s i n p r i m i s a t t e n t i o n e d i g n a evadit : fcilicet i : m o , q u o d P e t e c h i æ n u m e r o f i s f i m æ f a­ c i e m , q u a m alias r a r i u s i n f e f t a n t , o c c u p a r u n t , 2:do, q u o d

t o t v e l i c u l æ , f a n g v i n e repleta?, S y m p r o m a , q u o d n o v i ­ m u s , n o n nili in variolis o b f e r v a t u m , ortae f u n t (r); g:rio:

Pe

-(h) C o n f . H if tor ia m Fehris Tertian® Petechial, a N . D . Prae fide Mal- m o g i s e Scanor. oblervarse A n n o I 7 6 7 , in A c i . R e i . Acati. Scient. Stockb.

Vol. X X y I I I A l i a m e j u s m o d i Febris Intermirt. E p id e m ia m o b f e i v a v i t B o b s r r i o s I 7 8 4 > vires vero fpecifici e g r e g i e o b f e q u e n t e m . V i d . V o l . i i p. 3 7 2 . I nftitu t. M edie .

( c ) C a f u m feq ue nte m priori f o r m a f i m il e m , caufia ve ro differentem a d n o ta v i t N . D . Pr æs &s , M en fe Januarii 1 7 8 8 in fa m ilia q u a d a m ruri ha-,

b ita n te , p l u r i u m in fà n tu m m a x i m u s notu variolis pestimæ in d o l is , t u m Epi- d e m i c e g r a s fa n t i b u s , d e c u b u it . Q o u m j u f i u s aderat m etus, ne o m n e s e o ­ d e m m o r b o corriperentur, P u e r u m V I a n n o s n a t u m aliquot d i e s p oft in­ c e p t a m fratris s g r i t u d i n e m P r o p i n q u u s q u id a m , Upfa li® v i v e n s , d o m u m fe­ c u m du x ir , ut a prsrfentisfimo liberaretur p e r i c u l o ; at c o n t a g i o n e m fine d u b i o jam d u d u m forbuerat : n a m vix q u a t u o r h o r a r u m iter confecerat, q u u t n male habere incepit. D i e fequente d o l o r e s d o r f i , v o m i t u s , c u m f e ­ bre, et qua; f u n t reliqua fig na variolaruui, cru cia b a n t ; q u a m o b r e m nihil

o m n i n o , q u o d ad m i t i g a n d u m m o r b u m c o n d u c e r e po tuit , n e g l e & u m fuit. D i e vero I I l ; a debilitas infignis fupervenit et in facie E c h y m o f e s palpebrarum, Petechi® et Puftulat fan gvine® erupere, c u m f u m m a virium d efeftio ne. I V : a die E x a n th e m a h o c c e in p e fto r e q u o q u e brachiis « m a n i b u s confpicieba-

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P e te ch i as n o n ful> i n c r e m e n t o , aur flatu m o r b i , ut in aliis f eb r i bus m a l i g n i s fieri f o l e r , feci i n t e r ipfa initia et q u i d e m poft p r i m a m a c ce s fi on em in c o n f p e £ t u m venisfe.

4 :0 . E x a n t h e m a f y m p t o m a t i c u m o m n i n o , fed c r i t i c u m m i ­

n i m e fuisfe.

11 Icio. S i g n a , q u æ f a n g v i n i s d i s f o l u t i o n e m i n d i c a r e v u l g o c r e d i t u r , p r o r f u s d e f u e r e ; licet e n i m P e t e c h i æ , V i ­ bices , E c h y m o f e s et veficulæ f a n g v i n e æ o b f e r v a t æ fue­ r u n t , ramen f a n g v i s in veficulis inclufus, vel p e r E p i f t a x i n effufus, i n dol e fua g e n u i n a p r æ d i t u s erat, & cito in c o a g u l u m

abiit

[d).

A d f i n e m q u i d e m m a g i s tenui s evafir, c r u o r e

fcilicet h æ m o r r h a g i i s f r e q v e n t e r r e c u r r e n t i b u s amiffo, m a ­ g n o p e r e t amen ab illo, qui in f e b r i b u s m a l i g n i s v i d e r e eft, d if e r e p a n s . Se n te n t i a , q u a m de P e t e c h i a r u m a M i a s m a t e ex c o r r u p t i s h u m o r i b u s gafiricis o r t u , f o v e t CI. S t r a c k ,

m i n i m e heic q u a d r a t (V).

iVo. H i n c d e b i l i t a s v a f o r u m m i n i m o r u m c u t i s , m a ­ jori forfan jur e , causfa h o r u m E x a n t h e m a r u m p r o x i m a h a b e n d a e r i t ; h æ c e n i m v a f o r u m r u p t u r i s , quas in h o c cafu et q u i d e m fub p r i m o i m p e t u f e b r i s f i e r i , n e c e s f e eft, a n f a m p r æ b e t ; q u o fi t, ut & o r i a n t u r e x t r a v a f a t i o n e s et f a n g v i s fub e p i d e r m i d e e f f u n d a t u r .

V t o . A d h u c v a l d e d u b i u m effe v i d e t u r , an e r u p t i o ­ nes f e b r i u m P e t e c h i a l e s maffam f a n g v i n i s disfoluram caus- f a m a g n o f e u n t p r i m a r i a m . Cafus f u p r a m e m o r a r u s u n a c u m P h a e n o m e n i s in V a r i o l i s f a n g v i n e i s o b f e r v a ri s p o ­ tius d e m o n f t r a r e v i d e n t u r , causfam P e t e c h i a r u m p r o x i m a m i n d i m i n u t a vel d e p e r d i t a vitalitate v a f o r u m c u r a n e o r u m , m i n i m o r u m , qu a e re n d a m effe, et u n a m q u a m q u e f e b r i m ( m o ­ d o limul S y l t e m a N e r v o f u m p a t i t u r , ) in flatu fimili eas p r o c r e a r e poffe. I n f e b r i b u s fic di£lis m a l i g n i s , in q ui bus

B

Pe-(#/) Peliculas in f eb ribus, rtim f o l u t o t u m c o a g u l a t o f a n g v in e o h f e r v ,

M o r g a g n i in Sed. et Cnujf. M n rb . T . I I I . p. 9 .

(10)

P e t e c h i æ t a m v u l g a r e s , o m n i a S y m p t o m a t a , i n f i g n e t n a f t i o m s d e b i l i t a t e m S y f t ematis vafculofi a r g u u n t ; d u m c o n ­ t r a in febribus i n f l a m m a t o r i i s , in quibus & r o l u r et v i ­ talitas qvafi a b u n d a n t , n e m o , q u o d n o v i m u s , Pet;chias ob-

f e rva vit . Si i g i t u r in T y p h o m a l i g n a , F e b r i b u s E x a n t h e - maticis, aliisque e ju s de m indolis, P e t e c h i æ fub decurfu F e ­ bris, e u m p e r f p i c u i s disfoluti f a n g v i n i s fignis, a d i a r u e r i n r , i m m u t a t i o n e m h a n c maffæ f a n g v i n e æ a debiliori f i­ b r a r u m a & i o n e e f f e f t a m fuiffe, c e n f e n d u m efb. V e r u m in F e b r i b u s , q u a r u m diathefis P h l o g i f l i c a i n d o b e f t , di- v c r f a m p r o r f u s a d f p e £ t u m in d u i t l y m p h a .

V I . N o f t r æ q u o q u e o p i n i o n i f a v e t Febres P:techiales p r æ f e n s c u r a n d i m e t h o d u s , e x p e r i e n t i æ innixa N a m q u e m in f inem ftimulantia, eaque validisfima , V n u m fci- licet, t a m i n t e r n e d a t u m , q u a m fo ri n fe cu s a d m c t u m , A - eida m i n e r a l i a , O p i u m , S i n a p i s m o s , L a v a t i o n e s fr i g i d a s , ceteras, ad has febres f a n andas a d h i b e m u s , nifi it i n c i t e ­ t u r v a f o r u m a£bio, qua v i t a , q u o a d p a r t e m jan amiiTa, r e v o c a r i p o t e f t ; uti etiam p r o r r a & i o r i h o r u m medi a m i n u m ufii fuftentarur, d o n e c Crilis, q u o d e m u m c u m q u e n o d o ab- foluta fit? d u m ab altera p a r t e , ne u n ic a quidun p r o ­ babili r a t i o n e d e m o n f t r a r i p o t e f t , r e m e d i a finra l a u ­

data ad f a n g v i n e m diffolutum m u t a n d u m , c o rri de nd um ,

References

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