Questions Methods Evaluation Answers
I Can short daily
loading episodes improve tendon healing? Yes II Has loading different impact on early and late healing?
No
III Does unloading
influence ECM, inflammation and tendon genes during tendon healing? Yes IV Is the BMP- system regulated during tendon healing? By unloading? Yes No V Can myostatin stimulate tendon repair? Is it regulated by unloading? Yes Yes
VI How long does
the gene expression response last after loading? Gone by 24h.
Response to mechanical
Response to mechanical
loading in healing tendons
loading in healing tendons
Pernilla Eliasson
Pernilla Eliasson
Thesis at a glance:
Thesis at a glance:
Linköping University Medical Dissertations
No. 1247
Pernilla Eliasson Response to mechanical loading in healing tendons Linköping
201
1
Pernilla Eliasson Response to mechanical loading in healing tendons Linköping 2011
Linköping University Faculty of Health Sciences
Department of clinical and experimental medicine Division of Orthopaedics
Questions Methods Evaluation Answers
I Can short daily
loading episodes improve tendon healing? Yes II Has loading different impact on early and late healing?
No
III Does unloading
influence ECM, inflammation and tendon genes during tendon healing? Yes IV Is the BMP- system regulated during tendon healing? By unloading? Yes No V Can myostatin stimulate tendon repair? Is it regulated by unloading? Yes Yes
VI How long does
the gene expression response last after loading? Gone by 24h.
Response to mechanical
Response to mechanical
loading in healing tendons
loading in healing tendons
Pernilla Eliasson
Pernilla Eliasson
Thesis at a glance:
Thesis at a glance:
Linköping University Medical Dissertations
No. 1247
Pernilla Eliasson Response to mechanical loading in healing tendons Linköping
201
1
Pernilla Eliasson Response to mechanical loading in healing tendons Linköping 2011
Linköping University Faculty of Health Sciences
Department of clinical and experimental medicine Division of Orthopaedics