The involvement of clearance pathways and neuron-to-neuron transmission in Alzheimer’s disease

The results (Figure 3, A and B) demonstrate that 1 nM fibrillar Aβ40 significantly induced H3 acetylation and phosphorylation and furthermore, that 10 nM oligomeric

N-cadherin was expressed in neuron-glial and glial-glial adhesion in all tissues investigated; satellite cells envelop neural cell bodies of peripheral

Another autopsy study (Kurlander and Patten 1979) found significantly (p<0.05) elevated levels of Pb, Cu and Fe in dissected spinal cord anterior horn sections from ALS

A conclusion was made that γ-secretase activity, as measured by AICD production, decreased rapidly after short postmortem times, but was still detectable through all

• To study the proteome of a vulnerable, synapse-rich region of the hippocampus, which receives the crucial perforant path input, in order to identify proteins and pathways

Our study recognized that even though all enteric neurons and glia are generated from Ascl1 + progenitors, only specific subtypes of neurons expressing CALB1, TH and VIP require Ascl1

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This study was undertaken to measure concentrations of CgA, CgB, and NSE in a multi-center, retrospective material of serum and plasma samples taken at diagnosis in children with