Tyrosine Kinase Flt3/Flt3-Ligand Signaling in the Modulation of Immune Responses in Experimental Arthritis

To investigate the role of growth factor Flt3-L in human rheumatic disease levels of Flt3-L were measured in matched serum and synovial fluid samples from 130 RA patients and

Differentiation factor Fms-like tyrosine kinase 3 ligand is a modulator of cell responses in autoimmune disease..

Bhargava R, Gerald WL, Li AR, Pan Q, Lal P, Ladanyi M, Chen B: EGFR gene amplification in breast cancer: correlation with epidermal growth factor receptor mRNA and protein

A xenograft is transplanted either as a vascularised graft with a surgical anastomosis between the donor and recipient blood vessels (i.e. heart, kidney and liver), or as a free

rhamnosus GR-1 and other lactobacilli, with emphasis on elicited immune responses such as nuclear factor-kappaB (NF-κB) activation and cytokine release from human urothelial

The aim of this thesis was to investigate the role of Flt3 signalling for survivin production for arthritis development using the mBSA arthritis model and the role of survivin

The Freunds adjuvant supplemented with mycobacteria (complete Freunds adjuvant, CFA) was used to immunise the mice with mBSA (Paper I-II). Freunds adjuvant is a water-in-oil

Our in situ PLA experiments have indicated that formation of DEP-1-FLT3 complexes occurs at endogenous expression levels in the myeloid cell line THP-1 and that complex formation