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Immune cells and stem cells in spinal cord injury : defining spinal cord injury associated microglia

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IMMUNE CELLS AND STEM CELLS IN SPINAL CORD INJURY:

DEFINING SPINAL CORD INJURY

ASSOCIATED MICROGLIA

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Immune Cells and Stem Cells in Spinal Cord Injury:

Defining Spinal Cord Injury Associated Microglia

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ABSTRACT

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LIST OF SCIENTIFIC PAPERS

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ADDITIONAL CONTRIBUTIONS

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CONTENTS

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LIST OF ABBREVIATIONS

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(13)

INTRODUCTION

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β α

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(16)

α

(17)
(18)
(19)
(20)
(21)

α

γ

α

(22)

γ

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β

α β

β κβ

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(25)
(26)
(27)
(28)
(29)

β

(30)

β

(31)
(32)

β

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β

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γ γ

γ

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α

β β

α β

β

(36)

α β γ

(37)
(38)

γ α

α

(39)

γ

β α γ

β γ

β

γ

α κβ

α γ

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γ α

β β

β

γ β

α α

β

γ

β β

(41)

γ

α

β α

α

γ

γ

β γ

α β

γ α β

β γ

β

γ γ

β

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β

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α β

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α β

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α

β α

α β

(46)

α

α

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α β γ

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(49)

β

β

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β

β β

β

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AIM

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MATERIAL AND METHODS

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®

®

®

®

® ®

®

®

®

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α ®

®

® ®

®

®

α

®

®

®

α

β

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β

α

α

(60)
(61)

α

®

®

®

α

® ®

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α

®

®

®

(63)
(64)

®

®

®

®

®

(65)

®

®

®

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(67)

® β

®

®

®

ΔΔ

(68)

®

ΔΔ

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®

log2 (Rcij*106

TRcj +1) = log2(CPM+1) ≈ log2(CPM)

(70)
(71)
(72)

®

® ®

®

®

®

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®

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RESULTS

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α β α α

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γ β α

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γ

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DISCUSSION

.

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CONCLUSION

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OUTLOOK

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ACKNOWLEDGEMENTS

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FUNDING

CONFLICT OF INTEREST

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REFERENCES

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β

α

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α κ

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β

γ

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γ

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β

α β

β

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References

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