The importance of dendritic cells in IgE-mediated enhancement of the T cell response

Our interest in a specific B cell population arose with the discovery of murine autoreactive B cells, CD21 -/low cells, which expressed low surface levels or lacked the

CD23-mediated antigen presentation of IgE/Ag complexes by B cells prime T cells in vivo paper III A likely mechanism underlying IgE-mediated enhancement of the Ab response

Early in the development, the expression of a pre-B cell receptor (pre-BCR) with membrane-bound immunoglobulin (Ig) heavy chain protein associated with

(Greene, 2012) Transcription and translation of core clock components (CLOCK, NPAS2, BMAL1, BMAL2, PER1, PER2, PER3, CRY1 and CRY2) play a critical role in the generation of

DIN representerar Tyskland i ISO och CEN, och har en permanent plats i ISO:s råd. Det ger dem en bra position för att påverka strategiska frågor inom den internationella

The government formally announced on April 28 that it will seek a 15 percent across-the- board reduction in summer power consumption, a step back from its initial plan to seek a

The strength of this technique is proven for both membrane proteins (paper I) and for disordered proteins (papers II-IV), and the efficient incorporation of

NMR is the best and most suitable technique for investigating the details of this protein class, and cell-free protein synthesis (CFPS) offers several advantages compared

When this was tested experimentally, several lines of evidence suggested that CD11c + cells and not CD23 + B cells presented IgE-complexed Ag to CD4 + T cells in vivo 7 : (i)

Riksdagen ställer sig bakom det som anförs i motionen om att se över vilka möjligheter som finns för att ställa krav på föräldrar till unga som begått brott att delta och

Paper III shows an inhibitory role for CD36 on B cells in the autoreactive immune response to modified self-antigens with consequences for the subsequent expansion of activated B cell

To achieve this aim, the response to chemotherapy of the patients with follicular lymphoma was compared, the correlation of gene expression with survival of patients was

Figure 2. A) Antigen independent and dependent B cell development from pluripotent hematopoietic stem cells in bone marrow to terminal differentiated memory B cells and plasma

Detta tyder på att den maligna KLL cellen härrör från en B cell som är involverad i det medfödda immunförsvaret som fungerar som en första försvarslinje och som har till

Dendritic cells – which are CD11c hi – were depleted in the diphtheria toxin treated CD11c-DTR mice (Fig. 5A), whereas they are present in the untreated CD11c-DTR mouse (Fig. 5B)

Female WT and CR1/2-deficient DBA/1 mice were immunized with 20 µg BCII and spleen and lymph nodes were obtained 7, 10, 14, 28 and 56 days after immunization for analysis with

To demonstrate the importance of CD23 in IgE-mediated T cell activation ex vivo, CD23 -/- mice were immunized the same way as BALB/c mice (see above) and their splenocytes (crude)

We were interested to know if MZB cells can stimulate T-cells to produce specific cytokines that aid in breakage of tolerance and induction of inflammatory response in mouse model

We used a quantitative treatment of signaling to explore whether ligand discrimination and sensitivity would be achieved if TCR triggering was governed by receptor dwell time

Results and discussion IgE enhances specific antibody and T cell responses in mice overexpressing CD23 Paper I IgE-mediated antigen presentation in vitro is dependent on CD23+ B

Genom att vara medveten om de olika symtomen som kan vara relaterat till våld i nära relationer som litteraturstudien tar upp, kan det leda till att sjuksköterskor får lättare

För att undersöka chefernas syn på kommunikation ställdes frågan: ”Hur bör kommunikationskanalen användas?”, ”För vilken typ av information bör kanalen användas?”

Anhörigvårdarna uttryckte inte bara ett behov av information utan även en önskan om stöd från sjukvården till anhöriga (Ferrell et al., 2018; Leonidou & Giannousi, 2018)..