Björg Kristjánsdóttir Early Diagnosis of Epithelial Ovarian Cancer – Analysis of Novel Biomarkers2013

The exact impact of having a neonatal infection is difficult to define, since many of these infections affect infants with many other risk factors and complications, but in two

 To test the hypothesis that the biomarker HE4 and algorithm ROMA will improve early detection and differential diagnosis in an unselected population of women

Keywords: Ovarian neoplasms, EOC, diagnosis, protein biomarkers, CA125, HE4, Algorithms, RMI, ROMA, NGS, rare mutations, liquid

Aims: To explore ovarian cyst fluid as a source mining for new diagnostic biomarkers for EOC, and to validate the markers found together with CA125 (Paper I-III); and to evaluate

In a study by Moore et al., 1042 women with benign gynecologic disease were evaluated, and HE4 was less often elevated than CA125 (8% vs. CA125 is often increased in normal

1 Division of Innovative Care Research, Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden, 2 Stockholm Health Care Services

In the present study the relevance of HRNPM and SLC1A5 as prognostic factors for recurrent disease, survival and their impact on clinical and pathological features in a series of

In this thesis, by generating the oocyte-specific deletion of Rptor, Tsc2 and Pdk1 in mice, I have thus studied PI3K-mTORC1 signaling in oocytes in