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Fredrik Agholme

Fredrik Agholme

Linköping University Medical Dissertations No. 1253 Department of Clinical and Experimental Medicine

Linköping University, Sweden

Thesis at a glance

Question Methods Evaluation Answer Paper

I

II

III

IV

Does sclerostin- antibody treatment improve fracture healing?

Does dkk1-antibody treatment improve fracture healing?

Does this effect depend on mechanical load?

Does the effect of sclerostin-antibody treatment depend on mechanical load?

Do injury and change in mechanical load lead to changes in wnt signaling?

Yes

Yes/Yes

Yes

Yes

Wnt signaling and metaphyseal bone healing2011

(2)

Fredrik Agholme

Fredrik Agholme

Linköping University Medical Dissertations No. 1253 Department of Clinical and Experimental Medicine

Linköping University, Sweden

Thesis at a glance

Question Methods Evaluation Answer Paper

I

II

III

IV

Does sclerostin- antibody treatment improve fracture healing?

Does dkk1-antibody treatment improve fracture healing?

Does this effect depend on mechanical load?

Does the effect of sclerostin-antibody treatment depend on mechanical load?

Do injury and change in mechanical load lead to changes in wnt signaling?

Yes

Yes/Yes

Yes

Yes

Wnt signaling and metaphyseal bone healing2011

References

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