Measurements of the DNA double-strand break response

1) To investigate the influence of oxidative stress on the mtDNA replication replisome and the potential role of PrimPol as a translesion synthesis

In nuclear DNA, ribonucleotides are efficiently removed by the Ribonucleotide Excision Repair (RER) pathway and failure to remove them leads to human disease (e.g.,

Thus the aim set for the study was to investigate if DNA double-strand break repair mechanism is involved in chemically induced DNA heat-labile site removal. Degree project in

Cells exposed to a dose of 1 Gy high LET showed similar Mre11 foci formation after 130 minutes repair as cells exposed to 10 Gy low LET did (table 1 and comparison of figure 7e

This same technique was used for incorporating both the mutated Rad50 structure and the transition state like structure of Rad50 into the Rad50 wildtype electron density at 2.6

Also the importance of chemically and ionizing radiation induced HLS repair and transformation into DSBs in live cells was assessed in DSB repair inhibited cells. The activation

In the seven examples of concrete meanings not caused by physical impact there are three-four Swedish counterparts, which reveals that Swedish has fewer counterparts to the word

共a兲 Spectrum from the S 2p hole with minimum 10 eV Auger electron energy compared with simulated spectrum of selected doublet states only; 共b兲 the same experimental spectrum