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The treatment of both cancer pain and non-cancer chronic pain is still suboptimal. Using the clinical practice of intrathecal analgesia as a starting point, the overall aim of this PhD thesis was to conduct pain research at the interface between clinical pain medicine and the growing field of human proteomics. Hence, the cerebrospinal fluid is at the centre of the present dissertation, both as a target for infusing analgesics and as a potential biological fluid for human biomarker studies. Will it be possible in the future for pain physicians to prescribe analgesics on the basis of precise information generated by a panel of biomarkers?

The dissertation may perhaps been seen as a small step in that direction.

The Cerebrospinal Fluid in Severe

Pain Conditions

Linköping University Medical Dissertations No. 1465

Emmanuel Bäckryd

Emmanuel Bäckryd The cerebrospinal fluid in severe pain conditions 2015

FACULTY OF HEALTH SCIENCES

Linköping University Medical Dissertations No. 1465 Department of Medical and Health Sciences Linköping University

SE-581 83 Linköping, Sweden

www.liu.se

Clinical, Pharmacological

and Proteomic Aspects

(2)

The treatment of both cancer pain and non-cancer chronic pain is still suboptimal. Using the clinical practice of intrathecal analgesia as a starting point, the overall aim of this PhD thesis was to conduct pain research at the interface between clinical pain medicine and the growing field of human proteomics. Hence, the cerebrospinal fluid is at the centre of the present dissertation, both as a target for infusing analgesics and as a potential biological fluid for human biomarker studies. Will it be possible in the future for pain physicians to prescribe analgesics on the basis of precise information generated by a panel of biomarkers?

The dissertation may perhaps been seen as a small step in that direction.

The Cerebrospinal Fluid in Severe

Pain Conditions

Linköping University Medical Dissertations No. 1465

Emmanuel Bäckryd

Emmanuel Bäckryd The cerebrospinal fluid in severe pain conditions 2015

FACULTY OF HEALTH SCIENCES

Linköping University Medical Dissertations No. 1465 Department of Medical and Health Sciences Linköping University

SE-581 83 Linköping, Sweden

www.liu.se

Clinical, Pharmacological

and Proteomic Aspects

References

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