Marie Kalm Infl ammation and behavior following irradiation-induced injury in the developing brain

Modulating the immune response by deleting the third complement component, as in C3-deficient mice, revealed that they were, at least partly, protected from IR-induced injury to

One moderate dose of IR to the young rodent brain caused injuries that were detectable after several months, including impaired growth. We have shown that IR to the developing

The aim of the thesis was to investigate (1) the role of astrocyte activation and reactive gliosis in neonatal hypoxic-ischemic (HI) brain injury, (2) the role

The aim of the thesis was to investigate (1) the role of astrocyte activation and reactive gliosis in neonatal hypoxic-ischemic (HI) brain injury, (2) the role

the reduction in tissue loss, the injury to MBP and neurofilaments was also attenuated in MMP-9 deficient animals, which is similar to studies of focal cerebral ischemia in

Perinatal brain injury, as a result of hypoxia-ischemia (HI) or infection/HI, is a major cause of acute mortality and neurological morbidity in infants and children. The mechanisms

Interestingly, we observed differences between males and females in the acute phase after IR if the animals were pretreated with LPS 24 h before IR, where young females displayed

Looking at the long-term effects of IR we show that females display a more pronounced lack of growth in both the granule cell layer of the hippocampus as well as in the