Regulatory T cells and mucosal-associated invariant T cells in colon adenocarcinomas; Phenotype and function

However, the early bacterial gut colonization pattern was not related to the proportion of putative FOXP3 + CD25 high Tregs within the circulating CD4 + T cell population

This defect is most likely antigen- specific since CD25 + Treg cells from allergic individuals were able to suppress the production of IL-5 and IL-13 as well as IFN-

The unaffected colon mucosa display normal architecture with the epithelial lining (1) separating the intestinal lumen from the underlying lamina propria (2)

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higher expression of PD-L1, CD39 and CTLA-4 (Ahlmanner et al, unpublished). Perhaps blocking of only PD-1 is not efficient since Treg still can exert an immunosuppressive effect

In conclusion, this thesis demonstrates that Treg inhibit a Th1 associated anti-tumor response in intestinal tumors partly by reducing effector T cell accumulation. Strong

In this study, we used flow cytometry and flow cytometric cell sorting as well as in vitro cell culture assays to examine the phenotype and effector functions of two

It is known that boys have higher proportion of regulatory T-cells in peripheral blood (26, 27) and in cord blood (28) and the same for adults (29), but it is not studied if