issn 1652-4063
isbn 978-91-7668-905-9 Örebro Studies in Medicine 79örebro 2012
Doctoral Dissertation
Risk factors for cardiovascular events and incident
hospital-treated diabetes in the population
Payam Khalili Medical Science 2012
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ÖREBRO STUDIES IN MEDICINE 79Payam Khalili (1977) received his medical degree
at the Lund University in 2002. After two years of internship Payam began his training in Internal Medicine at the Central Hospital in Karlstad, Sweden. This training was completed in 2010 and Payam is currently working as a specialist in internal medicine and trainee in cardiology at the Department of Cardiology and Acute Internal medicine. His interest in cardiovascular research started during his medical studies when the first paper of this thesis was published in 2002. Payam Started his Ph. D. studies in 2007 at the School of Health and Medical Sciences at Örebro University with Professor Peter Nilsson as main supervisor. Cardiovascular disease (CVD) is the leading cause of death worldwide and well-established risk factors for CVD include increasing age, male sex, sedentary lifestyle, obesity, smoking, diabetes, hypertension, dyslipidaemia and low socio-economic status. These traditional risk factors do, however, not fully explain cardiovascular risk in general. In this thesis the focus has been on two conventional risk factors (smoking, blood pressure), and two unconventional risk markers (adiponectin, an adipocyte derived protein, and sialic acid, a marker of systemic inflammation) for prediction of CVD events. Two large-scale, population-based, screening studies with long follow-up periods have been used to study the role of these risk factors.
