Inflammation-Induced Gene Expression in Brain and Adrenal Gland

differentially expressed in the microarray analysis, all genes which in that analysis showed a fold change > 2 were examined, and with the exception for HSPs, to be

Modulating the immune response by deleting the third complement component, as in C3-deficient mice, revealed that they were, at least partly, protected from IR-induced injury to

One moderate dose of IR to the young rodent brain caused injuries that were detectable after several months, including impaired growth. We have shown that IR to the developing

LPS, when systemically administered, induce a systemic production of cytokines in blood borne cells, which can increase the permeability of the BBB and thereby permit

Interestingly, we observed differences between males and females in the acute phase after IR if the animals were pretreated with LPS 24 h before IR, where young females displayed

Together these results indicate involvement of the TLRs in rapid initiation of inflammation following HI and display active and prolonged participation of peripheral immune cells

Together, the results reveal novel gene functions during epithelial tube formation, and show that correct temporal unfolding of the tracheal gene network relies on

In paper IV, we show that ecdysone is required for the temporal unfolding of tracheal gene programs, including the expression of genes required for tracheal tube