SRP DIABETES WEBINAR
Diabetes caused by defects in the regulatory genome
Date: Friday, June 4, 2021, 12.00 –13.30 Place: Zoom webinar
Register in advance at this link
Host: Helena Edlund / SRP Diabetes
ANDREAS HÖRNBLAD
Assistant Professor Umeå University
See presentation of Dr. Hörnblad on next page
Gene regulatory mechanisms in development and disease JORGE FERRER
Professor
Centre for Genomic Regulation, (Barcelona), CIBERDEM, Imperial College London
See presentation of Dr. Ferrer on
next page.
SRP DIABETES WEBINAR
Professor Ferrer is chair in Genetics and Medicine, Head of the Section of Epigenomics and Disease, and Lead for Genetics and Genomics in the NIHR Imperial Biomedical Research Centre. He is also a Wellcome Trust Senior Investigator. He received his medical degree and trained in Endocrinology in the University of Barcelona School of Medicine. He subsequently trained in genetics and transcriptional regulation in Washington University and Harvard University before returning to Institut d’Investigacions Biomediques August Pi i Sunyer, Barcelona, and CIBERDEM. He then moved to Imperial College London where he established a laboratory based at Imperial Centre for Translational and Experimental Medicine. Since 2018, he is Senior Group Leader in Barcelona's Center for Genomic Regulation (CRG).
Professor Ferrer is interested in understanding genome regulation of
pancreatic beta cells and its implications for human diabetes. His team has combined genetic model systems and advanced genomics to address key questions in human beta cell biology, regeneration, and disease.
Jorge Ferrer, Center for Genomic Regulation Barcelona, CIBERDEM and Imperial College London
Andreas Hörnblad, Umeå Centre for Molecular Medicine, Umeå University
Andreas Hörnblad obtained his PhD in Molecular Medicine at the Umeå Centre for Molecular Medicine (UCMM) in 2012, studying the biology of the developing and adult mouse pancreas using 3D microscopy (Optical Projection
Tomography). During this period, he developed tools for spatial and
quantitative analysis of protein expression and applied this to mouse models of the developing and diseased pancreas.
After his thesis work, he was awarded a postdoctoral grant within the Marie Curie/EIPOD program to join the European Molecular Biology Laboratory (EMBL) in Heidelberg (Germany). This work focused on investigating the function of putative regulatory enhancers in the development of the limb and the brain using extensive in vivo genome editing approaches (CRISPR/Cas9).
In 2017 he joined the lab of Prof. Helena Edlund (UmU) for a second postdoc investigating mechanisms of ß-cell stress in obesity and type 2 diabetes. From late 2018 he is a principal investigator at UCMM and is currently focusing his research on enhancer function in development and disease, in particular their role in obesity associated liver cancer.
