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There are many people I want to thank for help and support during the years I have worked with this theseis. Mainly I want to thank:

Lennart Möller, my supervisor, for your advice, encouragement and great trust in me during these years.

My colleges and advisors Magnus Zeisig, Tim Hofer and Jonas Nygren, not least for teaching me the methods 32P-HPLC, 8-oxodG analysis and the Comet assay, respectively.

My colleges and great friends Eszter Nagy and Clara Johansson. What would I have done without your help with “a little bit of everything”? I’m so glad I have had the opportunity to work and laugh together with you.

The other nice persons in the AnTox group during these years, and other persons associated with the group, including Mary-Ann, Rikard, Eva, Ulf, Pontus, Therese, Karine, Staffan and Jeanette.

My collaborators and co-writers in the studies, mainly Anders Ljungman from Linköping University and also Åsa Holgersson at CCK, KI (I really appreciate all the laugh we had, and our great research findings of course…).

Christer Johnsson, at the City of Stockholm Environment and Health

Administration, Linda Johansson, at SP Swedish National Testing and Research Institute, and Mats Gustafsson, at the Swedish Road and Transport Institute, for providing the particles. Without them there wouldn’t have been much of a thesis.

The photographer Lennart Nilsson, for the excellent photos of the interaction between particles and lung cells, shown in the cover of this thesis.

My PhD-student friends at KI, mainly Anna-Karin and Rebecca for all nice chats over a cup of caffe latte, even though we have not had much time for that lately…

Also Lotta, not least for the nice company during our parental leave.

Carro, Cissi och Carina, my chemistry friends at Karlstad University, for making the studies so fun and easy. A special thank to Carro for being my room-mate in Australia (I still owe you for taking the bed leaving you with the mattress...).

My mum and dad, Birgitta and Ola, for always letting me do what I want and always being there when I need you. I also want to mention my sisters Lina and Kristin as well as my great parents “in law” Ulf and Cia. Thank you all for support and for taking such a good care of Lova.

Finally, my Man, husband, father of my daughter and best research supporter Mikael.

Thank you for always reading and commenting on my manuscripts as well as this thesis, and for inspiring me not only in research but also through life. Thank you for your endless Love and for giving me Lova. With you two by my side I think every day of how fortunate I am.

These studies were mainly financially supported by the Swedish Environmental Protection Agency, as well as Stockholm County Council and AF's

(Ångpanneföreningens) Foundation for Research and Development.

The author of this thesis, and the authors of the papers included in the thesis, are partners of ECNIS (Environmental Cancer Risk, Nutrition and Individual

Susceptibility), a network of excellence operating within the European Union 6th framework programme, priority 5: "Food Quality and Safety" (Contract No.

513943).

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