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It has been some very exciting, but also hard working years of both research and medical studies. I have learned a lot and made some very good friends! ! I would like to take the opportunity to thank some of you that have supported me thoughout these years:

Thomas Perlmann, my supervisor and head of the Institute, for accepting me as your PhD-student with a big smile, for teaching me what good science is about and for allowing me a high degree of professional freedom.

Ralf Pettersson, the former head of the Institute, for creating such a nice and stimulating atmosphere during your time as a head of the Institute. Elisabet Andersson, my cosupervisor, for good colaborations, nice travel company and fun chats! Thanks also for help with proof-reading of my thesis. Johan Ericson for fruitful colaborations. Jonas Muhr for your ability to explain complicated things very easy.

Also thanks to Ulf Eriksson, Kristian Pietras and the two new group leaders at LICR:

Susanne Schlisio and Jan Stenman.

To four amazing Drs: Theresa for always beeing there! For nice walks, breakfasts, lunches and fikas. It has been empty after you moved. Thanks also for your tremendous work with proof-reading of my thesis and for bringing the “PPPP- (Pasta-Paprika-Pinjenötter-Parmesan) dish” into my life. Jhansi for the time together at LICR, for a fantastic weekend in Brussels ! and for fun chats over skype. Magda for our time together as juniors and seniors in the labs, for answering all my thesis-related questions and for having such a sweet Sebbe! Tove for nice lunches while you were working at CMB, for fun company at the Keystone conference and for inspiring me to have a purple and turquoise thesis cover.

To the three sweetest persons at LICR: Maria for beeing my molecular biology expert, for all thousands of e-mails and sms, fun company during parties and conferences, for dinners at Tiffys ! and for caring about me. Banafsheh for your party-mood, your help with brain sectionings, stainings and pictures, for a very fun weekend in Brussels

! and for always lisening. Nick for beeing such a gentleman, for always waiting for me when I am late !, for taking your time and for calling me “stamcellsdrottningen”.

Idha, my bench neighbor, for nice small talks and for letting my stuff occupy your bench !. Magnus for helping me solve computer problems and for treating me with chocolate. Eva for talking as fast as me !, for always having time to answer questions and for excellent help with proof-reading of my thesis. Lia for small talks during looong cell culture sessions. Elisa for help with all kinds of things. Michal for solving complicated biochemical problems. Johan H, for your attitude and for informing me that you wrote your thesis in 48 hours !. Daniel for spending time during a weekend to proof-read my thesis. Carolina for entertaining me during cell culture sessions and for your inspirering personality. Monika for making long cell culture session fun. To Jamie, Nigel, Fred, Cecil, Ariadna and Hugo for bringing international atmosphere

into the lab. To Erika and Elisabeth for nice “tjej-middagar”. Etienne for your personality and your sence of humor !!

To the administration staff at LICR for your excellent way of running the Institute.

Inger for your ordering skills, for fun company and for arranging “tjej-middagar”.

Erika, Olle and Birgitta for your helpfulness. Charlotta for always having solutions to problems. Eva for beeing such a nice and helpful person. Mats thanks a lot for your help when my endnote crashed "!.

To former lab members; Sofia, Sanna, Alex, Elisabet, Mariette, Gerard, Bertrand, Åsa, Saga, Siqin, Lotta, Martin, Xuxia and Johan. Especially thanks to Sanna for hysterical primary culture dissection sessions ! and for keeping in touch after you left the lab. To Sofia for being the best student one can dream of! To Lotta for beeing my first supervisor and for teaching me how to grow cells. I´m much better now than I was in the beginning !. To Saga for teaching me the transplantation technique and for long, but nice days at the Neuro department. It was fun working with all of you!

To all present and past members at LICR!

To all members in the Johan Ericson lab, especially thanks to Ullis and Qialin for good colaborations and nice chats during operation days. To Zhanna for beeing such a helpful person, for good colaborations and for help with the cells. To José for taking your time to proof-read my thesis! To Matti for always having time to answer questions and for caring about all PhD-students. Also a big thanks for helping me with my thesis-application, without your help I would never have managed! To all people at CMB and members of DBRM.

To the people at the Neuro department! To the staff at the animal facility- especially thanks to Niklas, Tua and Anna, for taking so good care of my rats, for e-mailing me when new pups are born and for helping me with practical things. Thank you! To all rats and cells for beeing such pleasant to work with, for helping me obtaining good results and for your nice company. To our colaborators Abdeljabbar El Manira and Evanthia for excellent work with electrophysiology and for nice meetings! To Alexandra for being such a nice person and for your help and caring. To Birgitta Wester for always having time to perform FACS for me!

To our colaborators in the lab of Anders Björklund in Lund. Especially thanks to Anders for beeing such a nice and inspirering researcher and for help with pictures in the “thesis-kappa”. To Lachlan, Marie and Josephine for nice colaborations, excellent job with the transplantations and for fun company! To Manolo for running HPLC. To Bengt for help with pictures and for supplying me with “glas-kapillärer”.

To Laila Werner for your concern and for making the transfer of my studies from Uppsala to KI convenient.

During recent years, my life has not only consisted of science and studies !!:

Till Kristina/Kickan/CrazyK för att vi har känt varandra och hållit kontakten i 30 år trots att vi periodvis har bott i olika länder! För din spontana personlighet och roliga upptåg !. Till fikatjejerna Karin, Helena, Åsa, Kinga, Ingrid och Johanna för trevliga helger tillsammans, för roliga e-mails, för vilda ! fester och goda fikakvällar under studietiden i Uppsala. Till vettisarna Anna, Elisabeth, Ylva, Karin, Johanna, Carolina och Alexandra och till Malin ! för roliga fester på veterinärkåren, för valborgsfiranden (!) och för trevligt umgänge. Till Fredrik för alla cykelturer till och från BMC och för att vi hållit kontakten under åren.

Till Kerstin för att du har stått ut med orden: “Det knökar” ! och för ditt outröttliga sällskapsspelande. Till morbror Sten för din stora kunskap och dina roliga historier och till Ann-Marie för dina visdomsord. Även tack till mina ungdomliga gudmödrar med män: Inga-Lill och Lennart, Rosita och Jan, Dorothy och Hans.

!!! Till min kära familj för att ni alltid finns där! Till mamma och pappa för att ni har inspirerat mig till att läsa vidare, för all stöttning genom åren och för trevliga resor och somrar tillsammans! Anton för uppdatering på mode- och musikfronten och för dina försök att lära mig spela golf !. Oskar, Emma och Lisa för att ni flyttade till Sthlm! Oskar för äventyr i de värmländska fjällen, för joggingrundor och för våra

“sommar-tävlingar”! Emma för stöttning med läkarkunskaper och böcker och för att du har lärt mig att det går att använda både hopprep och golvmopp som sångmick! !.

Lisa för 31 år tillsammans ! men speciellt för tiden vi bodde ihop i Uppsala, för sällskap och TV-tittande genom telefonen och för att jag fått dela den senaste tidens hysteriska skrivande med dig och ditt pluggande! Också tack till Mathias och David för goda middagar och trevligt sällskap! Till Mikael för att du ställer upp för forskningen! För stöttning under perioder då jag både har pluggat och forskat, för att du de senaste månaderna har tagit hand om hushållet, för att livet med dig aldrig blir tråkigt ! och för att du är världens bäste! !!!

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