Molecular Pathways Mediating the Development of Female Germ Cells

The in vivo role of Sonic hedgehog (Shh) signaling during palatogenesis was assessed in K14- Cre;Shh c/c or K14-Cre;Shh n/c mice (Shh mutants), which lack Shh activity in both

This also changed the notion that OSCs might contribute to renewable of follicles as shown by OSCs purified from human and mouse ovaries by DDX4 antibody-based FACS..

This study revealed that Kitl expression in pfGCs is regulated by mTORC1 signaling in mice pfGCs and the suppressed of the awakening of oocytes in primordial follicles in pfGC- Tsc1

We have generated a conditional male germ cell-specific Dicer1 knockout mouse model where Dicer is deleted only in the germ cells.. Dicer1 knockout males are infertile and

Since we are interested in characterizing the role of Dicer-mediated pathways in male germ cell differentiation, RT-qPCR was carried out to detect Dicer

From this multi-step tumor progression view, a single gene defect cannot cause cancer, however, the frequency of mutated genes vary a lot.. For example, in colorectal cancers, a few

approval for research on somatic cell therapy and that it was sufficient to protect individuals from any risks posed by such research. While the rules that govern

Disease severity classification has been done according The Global Initiative for Chronic Obstructive Lung Dis- ease (GOLD) and includes stages I–IV, based primarily on pulmonary