14th International Congress ofRadiation Research

14th International Congress of Radiation Research

organized on behalf of the

International Association for Radiation Research

by the

Polish Radiation Research Society – memorial to Maria Skłodowska-Curie

in collaboration with the

Radiation Research Society

28 August – 1 September 2011 Warszawa

Poland

Dr. David Brenner (Columbia U) Failla Gold Medal

Dr. Marjan Boerma (U Arkansas) Michael J. Fry Research Award

Dr. Iris Eke (Oncoray) Jack Fowler Award

Alexandra Paun (McGill U) Marie Curie Award

Lisa Folkes (Gray Institute) Nucleic Acids Research Award

Dr. Albert Fornace (Georgetown U) SIT Excellence in Mentoring Award

Dr. Igor Shuryak (Columbia U)

Radiation Research Editors’ Award

Congress President: Antonina Cebulska-Wasilewska Chairman of the Organizing Committee: Marek K. Janiak Chairman of the Scientific Committee: Andrzej Wojcik

Representative of the Radiation Research Society: Jacky Williams

Honorary Committee

Dr Wojciech Bulski – President of the Society-Tribute to Maria Skłodowska-Curie

Prof. Katarzyna Chałasińska-Macukow – President of the Conference of Rectors of the Academic Schools in Poland

Prof. Andrzej Chmielewski – President of the Atomic Council of the Polish Atomic Energy Agency Prof. Hanna Gronkiewicz-Waltz – Mayor of the capital city of Warsaw

Prof. Michał Kleiber – President of the Polish Academy of Sciences (Chair) Dr. Ewa Kopacz – Minister of Health

Prof. Jerzy Kroh – Originator of the Polish school of radiation chemistry Prof. Barbara Kudrycka – Minister of Science and Higher Education Prof. Julian Liniecki – Nestor of nuclear medicine in Poland

Prof. Jerzy Niewodniczański – former President of the Polish Atomic Energy Agency Prof. Marian Reinfuss – National Consultant in oncological radiotherapy

Prof. Marek Rudnicki – President of the Federation of Polish Medical Organizations Abroad

Ms. Małgorzata Sobieszczak-Marciniak – Director of the Maria Skłodowska-Curie Museum in Warsaw Ms. Hanna Trojanowska – Undersecretary of State, Ministry of Economy, Government Commissioner for Nuclear Power

Prof. Michał Waligórski – former President of the Polish Atomic Energy Agency

Congress venue: Palace of Culture and Science (PKiN), plac Defilad 1, 00-901 Warszawa GPS coordinates: 52° 13' 54'' N, 21° 0' 23'' E

Organizing Committee

Marek K. Janiak (chair, Poland)

Ewa M. Nowosielska (secretary, Poland) Marek Bilski (Poland)

Aneta Cheda (Poland) Bruce F. Kimler (USA) Marcin Kruszewski (Poland) Paweł Kukołowicz (Poland) Anna Lankoff (Poland) Krzysztof Pachocki (Poland)

Wanda Stankiewicz-Szymczak (Poland) Jacky P. Williams (USA)

Jolanta Wrembel-Wargocka (Poland)

Executive Scientific Committee Andrzej Wojcik (chair, Sweden/Poland) Krzysztof Bobrowski (Poland)

Sandra Demaria (USA)

Bogusław Maciejewski (Poland) William F. Morgan (USA) Peter O´Neill (UK)

Herwig Paretzke (Germany) Kazuo Sakai (Japan)

Ewa Szajdzińska-Piętek (Poland) Elisabeth Travis (USA)

Jacky P. Williams (USA)

Vice chair: Ewa Szajdzińska-Piętek (Poland) Vice chair: Jacky P. Williams (USA)

Committee members Dietrich Averbeck (France) Eduard Azzam (USA) Dimitry A. Bazyka (Ukraine) Adrian Begg (Netherlands) S?ren Bentzen (USA)

Krzysztof Bobrowski (Poland) David Brenner (USA)

Martin Brown (USA) Elisabeth Cardis (Spain) Ian Carmichael (USA)

Antonina Cebulska-Wasilewska (Poland) Eun Kyung Choi (Korea)

Sandra Demaria (USA) Marco Durante (Germany) Anna Gasińska (Poland) Gianfranco Grossi (Italy)

Mats Harms-Ringdahl (Sweden) Kathy Held (USA)

Jolyon Hendry (UK) Georg Iliakis (Germany) Victor Ivanov (Russia) Kazimierz Jeleń (Poland) Michael Joiner (USA) George Don Jones (UK) Yosuke Katsumura (Japan) Kalina Kawecka-Jaszcz (Poland) Jin Kyu Kim (Korea)

Jon Klauenberg (USA) Amy Kronenberg (USA) Michael Kundi (Austria) Shu-Zheng Liu (China)

Bugusław Maciejewski (Poland) André Maisseu (France)

Julian Malicki (Poland) Roger Martin (Australia) Viktor Meineke (Germany) Kaushala Prasad Mishra (India)

Ronald Mitchel (Canada) William F. Morgan (USA) Mehran Mostafavi (France) Carmel Mothersill (Canada) Tulsi Mukherjee (India) David Murray (Canada) Andrzej Niemierko (USA) Peter O'Neill (UK)

Takeo Ohnishi (Japan) Paweł Olko (Poland) Koji Ono (Japan)

Deborah Oughton (Norway) Jens Overgaard (Denmark) Herwig Partzke (Germany) Simon Pimblot (UK) Wendy Pogozelski (USA) Mohi Rezvani (UK)

Hans-Peter Rodemann (Germany) Janusz Rosiak (Poland)

Laure Sabatier (France) Kazuo Sakai (Japan) Sisko Salomaa (Finland) Giustina Simone (Italy)

Krzysztof Składowski (Poland) Peter Sminia (Netherlands)

Synnöve Sundell-Bergmann (Sweden) Stanisław Szmigielski (Poland) Iza Szumiel (Poland)

Gisela Taucher-Scholz (Germany) Hubert Thierens (Belgium) Elisabeth Travis (USA) Ingela Turesson (Sweden) Richard Wakeford (UK)

Albert van der Kogel (Netherlands) Philippe Voisin (France)

Marie-Catherine Vozenin-Brotons (France)

Friedo Zölzer (Czech Republic)

AINSIE: Australian Institute of Nuclear Science and Engineering ARR: Association for Radiation Research

ERRS: European Radiation Research Society FNP: Polish Science Foundation

IARR: International Association for Radiation Research POLATOM: Radioisotope Centre (Poland)

NVRB: Dutch Radiation Research Society

PTBR: Polish Radiation Research Society PTChem: Polish Chemical Society RRS: Radiation Research Society

SAR: Sociedad Argentina de Radioprotección SFR: Swedish Society for Radiation Biology SIRR: Italian Society for Radiation Research

WIHiE: Military Institute of Hygiene and Epidemiology (Poland) Delphine Denoyer

Olga Martin Pavel Lobachevsky

Supported by ARR Early Career Investigators Hayley Furlong

Jonathon Coulter Melvin Chua Scott Bright Simon Horn Sylwia Kabacik General Awards Peter Wardmann Ian Stratford Siobhan Cunniffe Don Jones

Supported by ERRS Anna Acheva

Gerben Borst Alsu Dyukina Asal Fotouhi

Adamantia Fragopoulou Charlotte Rombouts Alexandra Somsedíková Elina Staaf

Ramesh Venkata Yentrapalli

Supported by FNP Kamil Brzóska

Marta Deperas-Kamińska Dorota Dziuban

Chitho Feliciano Leszek Grzanka Marta Korcyl Amit Kunwar Ewelina Lipiec Milena Marszałek Justyna Miszczyk Agnieszkat Panek Kinga Polaczek-Grelik Tadeusz Strózik Aneta Węgierek-Ciuk Paweł Wroński

Oscar Ardenfors Dmitry Artamonov Artak Barseghyan Christina Bauernschmidt Eliana Beltran

Audrey Bouchet Karl Butterworth Jennifer Fazzari Monika Frenzel Christina Ganzha Aleksandra Gruca Susan Howett Chao-Yin Huang Wendy Hyland Amit Kumar Yu-Chuan Lin Yuan-Hao Liu Fiona Lyng Aimee McNamara Natalia Niewidok Giacomo Pirovano Sylwia Ptasinska Anne Sanders

Adriano Márcio Santos Mukesh Kumar Sharma Laura Taggart

Reeta Tiwari Yusuke Urushihara Amit Verma

Supported by NVRB Martti Maimets

Ricardo Alexandre Leite Sonja van der Veen Ingar Seemann

Supported by POLATOM Abdullah Farooque

Supported by PTBR Krzysztof W. Fornalski Jacek Grębowski

Supported by PTChem Agnieszka Sulich

Jennifer Anderson Narongchai Autsavapromporn Samaneh Baradaran Antonella Bertucci Payel Bhanja Paul Black

Manuela Buonanno Chun Chen

Fanghsin Chen Sarah Cooper Jonathan Coulter Kamal Datta Jennifer Dickey Barbara Dziegielewska Iris Eke

Cristian Fernandez Lisa Folkes Sheng Yung Fu Geraldine Gonon Dana Greene-Schloesser Caroline Hadley

Carla Hajj Deping Han Amol Hosing Matthew Howland Isabel Jackson Elzbieta Jagielska Hedieh Katal Mohseni Zana Kepuska

Svetlana Khoronenkova Gabriel Krigsfeld Martin Lawlor Yuan-hao Lee Chang-Lung Lee Alexandra Litvinchuk Christin Lund-Andersen Balázs Madas

Tytus Mak Adeola Makinde Casey Manning Carlos Daniel Martins Barbara Meyer Caitlin Mills Vijayalakshmi Mohanseenivasan Elizabeth Moore

Moon-Taek Park Zarana Patel Alexandra Paun Anita Peoples Scott Peslak Ianik Plante Yelena Rivina Subhrajit Saha Merriline Satyamitra Igor Shuryak Brock Sishc

Malgorzata Smialek-Telega Shubhankar Suman Joshua Swift Juliana Tafrova Kristina Taylor Colman Trainor Ivelina Tsacheva Sonja van der Veen Jamunarani Veeraraghavan Xiao-Chun Wang

Shu-Chi Wang Richard Watson Jeffrey Willey Ching-Fang Yu

Supported by SAR Cristina Gallegos

Supported by SFR Karl Brehwens

Supported by SIRR Ilaria Improta Luca Mariotti Maurizio Marrale Nafiseh Mirzajani

Supported by WIHiE Yi-Chun Lin

Alexey Moskalev

Andreyan Osipov

Abhay G. Puthli

Andrian Yavnyuk

hou rs T hu rs d ay 01 .09 .2011 W e dn es d ay 31 .08 .2011 E ye op e n e rs ( EO 18 -EO 23 ) C o ff ee b reak S und ay 28 .08 .2011 M ond ay 29 .08 .2011 T u es d ay 30 .08 .2011 08 :00 -09 :00 08 09 :00 -10 :00 09

E ye op e n e rs ( EO 1 - EO 6 ) C o ff ee b reak E ye op e n e rs ( EO 13 -EO 17 ) C o ff ee b reak

E ye op e n e rs ( EO 7 -EO 12 ) C o ff ee b reak 10 :00 -11 :00 10 11 :00 -12 :00 11

S y m po s ia ( S 1 - S 6 ) S y m po s ia ( S 19 -S 24 ) S y m po s ia ( S 13 -S 18 ) S y m po s ia ( S 30 -S 35 ) 17

16 :00 -17 :00 17 :00 -18 :00

12 :00 -13 :00 RR S a w a rd lec tu re ( PL 4 ) L un c h b reak po s te r sess ion s (POS 23 -POS 29 ) S y m po s ia ( S 7 -S 12 ) F ree ti m e

L un c h b reak 19 :00 -20 :00

12 13 :00 -14 :00 13 R e gi s tr a tion

14 :00 -15 :00 14 15 :00 -16 :00 15 16 21 :00 -22 :00 21

18 :00 -19 :00 20 :00 -21 :00 C ong ress g a la dinn e r 19 :30 - 24 :00

19

O p e ni ng ce re m on y W e lc o m e rece p tio n 20

18

L ec tu re a bou t M a ri e S k odow ska -C u ri e ( PL 7 ) C o ff ee b reak ICRU a w a rd lec tu re ( PL 2 )

P o s te r sess io n s (POS 14 -POS 22 ) C lo s ing ce re m on y

C o ff ee b reak

C on fe re n ce lec tu res (C L 1 - C L 6 ) C on fe re n ce lec tu res (C L 7 -C L 12 ) C on fe re n ce lec tu res (C L 13 -C L 18 ) L un c h b reak C o ff ee b reak S y m po s ia ( S 25 -S 29 ) F u k u s hi m a nu c lea r pl a n t acc id e n t lec tu re ( PL 1 ) P o s te r sess ion s (POS 1 -POS 13 )

L un c h b reak C o ff ee b reak P o s te r sess ion s (POS 30 -POS 41 ) ICRR 2011 d e b a te ( pl e n a ry )

AR R a w a rd lec tu re ( PL 5 ) E RR S a w a rd lec tu re ( PL 6 )

IAR R a w a rd lec tu re ( PL 3 )

St ar t tim e Sunda y 2 8 A u gus t 2011 1 8 :0 0 O p en in g cerem on y an d w el com e rece p ti on ( L R 1 K o n greso w a) C h ai r: M arek K J an iak ( P ol an d ) A d dres se s: M aci ej ż yl ic z, A d vi so r t o B ro n isław K om or o w sk i, P re si d en t o f P ol an d , W al d em ar Paw la k, M in is ter o f E con om y, H o n o ra ry P at ro n o f I C R R 2011 H ann a G ro n ki ew ic z- W al tz , M ayor of the c ap it al c it y o f W arsaw M ichał K lei b er , P res id en t of t h e Po li sh A cadem y of S ci en ces O h ts ur a N iw a, Pr es id en t o f IA R R A n to n in a Cebul sk a- W as il ew ska, Pr es id en t o f IC R R 2011 S tage perf or m an ce b y th e P ol is h f ol kl or e d an ci ng g ro u p P R O M N I W el co m e r ec ep ti on i n t h e f oyer of L R 1 K o n gr es o wa A crony m s: CL – C on fe re n ce l ec tu re CR – Cof fe e a n d l u nc h ro om E O – E ye o pene r L R – L ec tu re ro om M R – M ee tin g ro om PL – Pl en ar y l ec tu re P O S – P ost er se ss ion PR – P os te r roo m S – S ym p os iu m

L ect u re room s: L R 1 K ong re so w a L R 2 R at u szow a LR 3 Sk ło d o w sk a L R 4 W arszaw sk a LR 5 M ik oł aj ska L R 6 K ruc zkow sk i Po st er r oom s: PR 1 S ta rz yńs ki PR 2 Br o n ie ws ki

C of fee an d l u n ch room s: C R 1 M ar m ur ow a C R 2 K o rcza k M eet in g ro om s: MR 1 R u d n ie w MR 2 R u d n ie w a n n ex M R 3 – M R 5 W arszaw sk a annexe MR 6 P u szk in Pl ea se s ee rear p ar t of t h e b o ok f or a la you t of t h e r oo m s a n d a n e xp la n at io n of t h e ro om na m es .

St ar t tim e M o n d ay 29 A u gu st 201 1 R O O M L R 1 K ongre so w a L R 2 R at u szow a L R 3 S k ło d o w sk a L R 4 W arszaw sk a L R 5 M ik oł aj sk a L R 6 K ru czk ow sk 08: 30 E ye o p en er l ec tu re s E O 1- E 0 6 EO1 . C h ai r: M. K . Ja n ia k S . Ak ib a ( Ja p an ): Low -l ev el ra d ia ti o n e xpo su re an d can ce r ri sk .

EO2 . C h ai r: H. T an o ok a M . At ki ns o n ( G er m any) : T h e ge ne ti cs o f ra d iat io n in d u ce d ca n ce r.

EO3 . C h ai r: A . O tt ol en gh i E . Gu d o ws ka -N o w ak (P ol an d ): M od elli n g ra d io b io lo gi ca l r espon se s: w h er e are w e?

EO4 . C h ai r: S . C h an d n a Y . W ang (U SA ): O u tl in e t h e ro le a n d i m p o rt ance of m ic roRN A s i n c el l fu nc ti on in cl u d in g re sp on se to r ad ia ti on .

EO5 . C h ai r: M. K ru sz ew sk i G . B auer ( G er m any) : R eacti ve o xy ge n an d n itro ge n sp ec ie s i n vo lv ed in r ad ia ti on- in d uced si gna ll ing/ b ys ta n d er ef fe ct s.

EO6 . C h ai r: K . B ob ro C . C h at gilia lo gl u (Ita Chem ic al r adi at io n s re la te d to r ad ic al- b as D N A da m ag e. 09: 30 C of fe e b re ak ( C R 1 M ar m u ro w a a n d CR 2 K orc za k) 10: 00 S ym p os ia S 1 – S 6 S 1 . N orm al tis su e e ffe ct s of r adi at io n C h ai r: M . R o bbi ns , J. W illi am s 10: 00 C. Li m ol i ( U S A ): S tem C ells , O xi d at iv e S tr es s, and N or m al Ti ss u e I n ju ry . 10: 25 M . R ob b in s ( U S A ): U se of a n ti -i nf la m m at o ry th er ap ie s t o m odul at e ra di at io n -i n du ce d la te ef fe ct s. 10: 50 M .C . Voz en in (F ra n ce ): I n fl amma ti o n and f ib ro si s 1 1 :1 5 K . F le cken st ei n (G er m an y): H yp ox ia a n d in fl am m ati on i n ra d iat io n in d u ce d n or m al tissu e in ju ry .

S2 . Chr om at in m od if ic at io n s and D N A da m ag e r es p on se C h ai r: I . Szum ie l, J. D ob ruck i 1 0 :0 0 J . D ob ruck i ( P ol an d ): H istone m et h yl at io n a n d het er oc hr om at in p rot ei n 1 in D N A d am age re sp on se. 10: 25 T. P andi ta ( U SA) : C h ro m at in m odi fi ca tio n s and D N A d am age r es p o n se . 10: 50 J. R . M o rri s (U K ): Re gu la ti on o f p os t- tr an sl at io n al m odi fi ca ti on s in t h e d oubl e-st ra nd break re sp o n se . 11: 15 M . F al k (C ze ch R ep u b lic ): In d u ct ion, re p air a n d m is re p air o f D N A doubl e- st rand br ea ks (D SB s) i n t h e c o nt ex t o f hi gh er -o rd er c h ro m at in struct ure.

S 3 . S p ace resea rc h Ch ai r: F . Cu ci n ot ta , M .A . T abocchi n i 1 0 :0 0 F . C u ci n otta (U S A ): In tr o d u cti on 10: 10 G . Z h ou ( C hi n a) : D if feren t r es p on se s be tw een G 0 a n d ex p o ne nt ia ll y gr ow in g c el ls e xp os ed to i o n iz in g ra d ia ti on . 10: 30 M .A . T abocch in i (Ita ly ): D N A da m ag e an d re p air a ft er l o w d os es of c h ar ge d p artic le s. 10: 50 J. P lu th ( U S A ): R ad iat io n qual it y de p enden t ef fe ct s on ph os p h oryl at io n ki ne ti cs of prot ei n s i n vo lv ed in e ar ly D N A d am ag e re sp o n se . 11: 15 M .K . O 'B an io n (U S A ): H ippo cam p al n eur o ge nesi s and con te xt u al f ea r re sp o n se i n C 5 7 B L /6 mi ce ex p ose d t o 2 G y w h ol e body p ro to n s.

S4 . R ad ia ti o n a n d im m u n e res p onse m o d if iers C h ai r: E . R epasky, S. D em ar ia 10: 00 E . R epas ky ( U S A ): D ef in ing a r ol e f or body te m p er at ur e i n cy to ki ne re gu la ti on and neut ro p h il h om eo st asi s f ol lo w in g to ta l body i rr adi at io n . 10: 25 S . D em ar ia ( US A ): C an ce r ce ll s str es se d b y ra d io therapy be co m e ta rg et s fo r C D 8 T ce lls a ct iv ate d by ant i- C TL A -4 tre atm en t. 10: 50 J. W . H o d ge ( U S A ): Th e t ippi ng p oi nt f or co m b in at io n th er apy: can ce r vacci n es wi th ra d ia ti o n . 11: 15 C .- S . C h ia n g (T ai w an ): D istin ct in v iv o re sp o n se s o f tu m o r- asso ci ated m ac ro phages to i rra d ia ti o n .

S5 . RR S P re si d en t's sy m p os iu m - b iol og ic al si gn ific an ce o f co m p le x D N A d am ag e: p h ysics, ch em is tr y a n d b iol og y of c om p le x dam age Ch ai r: P. O’ N ei ll 1 0 :0 0 A. O tt ol engh i (Ita ly ): M ode ll ing o f D N A dam ag e d epend en ce o n ra d iat io n qual it y. 10: 25 M . Lo m ax ( U K ): The p ros a nd c o n s of pr oc es si ng c lu st er ed D N A da m ag e si tes . 10: 50 K . E lm ro th ( S w eden ): For m at io n a n d cons equ enc es o f co m p le x D N A le si on s u si n g radi at io n wi th d if fe re n t L E T . 11: 15 A . G eo rg ak il as ( U S A ): N ew in si gh ts i n to th e p ro ce ss ing o f oxi d at iv el y in d u ce d cl us te re d D N A le si o n s. C li n ic al app li cat io n s?

S6 . R ad ia ti o n d am ag to b io m ol ec u le s (I): p ep ti d es , prot ei n s, me mb ra n e l ip id s Ch ai r: C. F er re ri , K. B ob ro w sk i 10: 00 E .F . G ar m an ( U R adi at io n da m ag e in m ac ro m ol ec u la r crys ta ll ograp h y: curren t c h al le nges . 10: 25 W .H . K opp eno (S w itz er la n d ): F or m at and r epai r of p ro te in ra d ic al s. R ole o f th iy l ra d ic al s. 10: 50 B . M ih al je vi c (C roat ia ): A n ew b io m m o d el o f fr ee radi cal re ac ti vi ty i n l ip ids . 11: 15 M . S tuar t ( C anada) F att y a ci d c om p ositi on m u sc le tissu e m ea sured am p h ib ia n s liv in g in ra d io log ic al ly c on tam and no n- co n tam in at ed en vir on m en ts. 1 2 :0 0 C on feren ce l ec tu res C L 1 – C L 6 CL1 . Ch ai r: I . G u se va Ca nu R . W ak eford ( U K ): Cher no by l e ff ec ts : w h at do w e know af te r 25 ye ar s?

CL2 . Ch ai r: A . H aim ov it z- F rie d m an N . C ordes (G er m any ): A s ti cky m at te r: E C M and r ad iat io n c ell s u rv iv al .

CL3 . Ch ai r: I . S tr at fo rd S. F o rm en ti ( U SA) : C li n ic al r el evan c of t h e im m une re sp o n se .

C L 4 . C h ai r: B . C ed erval l C . M ot h er sill (C an ada) : C h ron ic e xpo su re s, m u ltip le stre ssors a n d ot h er u n co m for ta b le i ssu es in r adi at ion pr ot ec ti o n .

C L 5 . C h ai r: A . L anko ff H . S h en (U S A ): N ano te chn ol og y in c an ce r th erap y.

CL6 . Ch ai r: W .H . K o C. H ou ée L ev in ( F ra nc P ro te in ra d ia ti on ch em on e el ec tr on o xi d at io me th io n in e i n pept id and prot ei n s.

St ar t tim e M o n d ay 29 A u gu st 201 1 1 3 :0 0 Lunc h br ea k ( C R 1 M ar m u ro w a a n d C R 2 K or cz ak ) 14: 00 P le n ar y le ct u re P L 1 ( L R 1 K ongres ow a) C h ai r: C . S tr ef fe r ( G er m an y) T. O h n is h i ( Ja p an) : D is as ter o f Fuku sh im a- D ai ic h i nuc lea r p o w er p la n t ( Japan) by eart hq uake a n d ts u na m i a n d R I- p ol lu ti on . 15: 00 P os te r s es si o n s P O S 1 – PO S 13 ( P R 1 S ta rz yń ski a n d PR 2 B roni ew ski ) P O S 1 A d ap ti ve r es p on se ; P O S 2 B io log ic al do si m et ry ; P O S 3 B ys tander ef fe ct s; P O S 4 Ce ll s ign al li ng ; P O S 5 E ff ect s o f ra d iat io n o n i n fl amma ti o n a n d i mmu n it y; P O S 6 Co m p ut at io n al /t h eo re ti cal s tu d ie s i n ra d iat ion physi cs a n d c h em is tr y; P O S 7 R adi at io n chem is tr y and s p ac e r es earc h ; P O S 8 R ad ia ti on ch em istry o f b io ac tiv e co m p ounds P O S 9 : B or on neut ro n ca p tur e t h erapy ( B N C T ); P O S 1 0 E p id em io lo gy ; P O S 11 M ol ecu la r i m ag in g i n d ia gno si s a n d t h erapy; P O S 1 2 H ad ro n th erapy ; P O S 1 3 In te rd is ci p li n ary st u d ie s. Au th or s o f od d p os te r nu m b er s ar e as ke d t o b e at t h ei r po st er s fr om 15: 00 t o 15: 45 A u th or s o f ev en p os ter num b er s ar e a sked t o b e a t t h ei r p ost er s fr om 1 5 :4 5 t o 1 6 :3 0 16: 30 C of fe e b re ak ( C R 1 M ar m ur o w a and C R 2 K or cz ak ) 17: 00 P le n ar y le ct u re P L 2 ( L R 1 K ongres ow a) C h ai r: H an s M enzel ( S w it zer land) D u dl ey G o od hea d ( U K ): On t h e t ra ck t o c lu st er ed d am ag e an d r ad ia tio n e ffe cts. IC R U L .H . G ra y a w ar d l ec tu re . 18: 00 S ym p os ia S 7 – S 1 2 S 7 . A d va n ces in c om b in ed th erap ie s: i on izin g rad iat io n , h yp er the rm ia and c h em ot he rapy Ch ai r: E . Az zam , E. A. R apas ky 18: 00 F . W enz (G er m an y) : Co m bi n ed rad io -x yz-t he ra p y. A c li n ic al p er sp ec tive . 18: 30 Z . V u ja skovi c ( U S A ): Com b in ed t h er ap ie s i n tre atm en t o f b la d d er c an ce r. 19: 00 E. A . R ep as ky ( U S A ): Ca n t ar get in g no rm al , h om eo sta tic vas om ot or fu nc ti on b y m il d hype rt h er m ia r es u lt in im p ro ve d re sp o n se s t o ra di at io n or c h em ot h er ap y?

S 8 . E n viro n m en ta l ra d io b iolo gy Ch ai r: C . M ot h er si ll, D. Ou gh to n 18: 00 M . S tuar t ( C anada) : Ad ap tive re sp on se s an d b ystan de r e ff ect s in a m u ltip le s tr es so r c on te xt . 18: 20 T .G . H in ton ( F ra n ce) : L esso n s Le ar ne d… .Less on s Los t… .O b se rvati o n s i n Ra d ioec ol o gy 25 Yea rs af te r Ch er n ob yl . 18: 40 G . R udol fs en (N orw ay ): C h er n obyl bi rd s. 19: 00 D . O ught on ( N or w ay) : R ad iat io n e ff ect s on e ar th w or m s.

S 9 . D ose s rece iv ed f ro m mo d er n me d ic al pr oc ed u re s Ch ai r: S . M at tsso n , A. Al m én 18: 00 A . A lm én ( S w eden) : Di ag no st ic ra d io log y and in te rv en ti on al p ro ced ur es . 18: 30 S . M at tsso n (S w ed en ): Nu cl ea r m ed ic ine f or di ag n os ti cs and th erapy. 19: 00 W. B u ls ki ( P ol an d ): Do se s f ro m rad io th erap y.

S 1 0 . A u to p hagy : a d ou b le-e d ged sw or d in ce llu la r ra d ia ti on r esp on se C h ai r: B .G . W ou ters, D. Ch an 18: 0 0 B .G. Wo u te rs (C anada) : T h e u n fo ld ed pr ot ei n r es p ons e e n ab le s hi gh r at es o f aut op h ag y and prot ec ti on a gai n st me ta b ol ic stre ss in t u m ors. 18: 3 0 D . C han ( U S A ): In d u ct io n of aut o p h ag ic ce ll deat h i n r enal c el l carc in om a. 19: 00 H . K im ( U S A ): R ad iat io n do se p ro te ct io n and m it ig at ion b y C arbam aze p in e (C B Z ) is a u to pha gy i n d ep ende nt .

S 11. R ad ia ti o n da m ag e to b iom ol ec ul es (II) : nuc le ic ac id s and t h ei r co n stitu en ts Ch ai r: M .D . S evi ll a, T . M aj im a 18: 00 T . M aj im a ( Ja p an ): Ch arge t ra n sf er i n D N A . 18: 3 0 A . A d h ik ary ( U S A ): For m at io n of r adi at io n- in d u ce d D N A s u ga r- phos p h ate b ack bo n e ra d ic als v ia i o n iz at io n and exci ta ti o n p ath w ay s. 19: 00 D . H un ti n g ( U K ): H o w c an w e ex pl oi t th e p rop ert ie s o f lo w e nergy and h yd rat ed e le ct ro n s to i m prove ra d io the ra py ?

S 12. E th ic s of ra d ia ti p rot ec ti on Ch ai r: F . Z öl ze r, C . S 18: 00 C. St re ff er ( G er m Et hi cal as pect s and cul of r adi ol og ic al pr ot ec in m ed ic in e and re se arch 18: 30 J. Lo cha rd ( F ra The et hi ca l f ounda ti o n of t he r ad ia ti o n p ro tec sy st em . 19: 00 B . T aebi (N et he rl ands ): E thi cs ra d io log ic al p ro te ct io n u cl ea r pow er p ro d uc and w as te m an ag em en

St ar t tim e T u es day 30 A ugust 201 1 R O O M L R 1 K ongre so w a L R 2 R at u szow a L R 3 S k ło d o w sk a L R 4 W arszaw sk a L R 5 M ik oł aj sk a L R 6 K ru czk ow sk 08: 30 E ye o p en er l ec tu re s E O 7- E O 12 EO7 . C h ai r: M . A tk in so n J. W illi am s ( U S A ): A n im al m odel s: t h e g o od , th e b ad a n d th e u se le ss .

EO8 . C h ai r: W . Bl ak el y K. R ot h ka m m ( U K) : Adv anc es i n bi ol o gi ca l in d ic at ors o f ra d ia ti o n ex p os u re .

E O 9 . C h ai r: W .F . M organ O . K oval chuk (C an ada) : R adi at io n i n du ce d ep ig enet ic ef fe ct s.

EO 1 0 . C h ai r: M . H ar m s- R in gdahl G . H il debran d t ( G er m any) : R adi at io n -i n du ce d card io va sc u la r e ff ect s.

EO 1 1 . C h ai r: E. S za jd zi n sk a- P ię te k P. W ar d m an ( U K ) R ad ia ti on chem istry i n th e 2 1 st ce n tury: curr en t st at u s and pers pect iv es .

E O 12 . C h ai r: S . P tas P . D en ifl (A u stri a) : E d ri ven r eact io n s i n d hel iu m nan o d ro p let s – i n vest ig at io n s on t h e r adi at io n da m of bi om ol ec u le s. 09: 30 C of fe e b re ak ( CR 1 M arm urow a and C R 2 K o rczak) 10: 00 S ym p os ia S 13- S 1 8 S 1 3 . N ew m o d al itie s fo r can cer t re at m en t Cha ir : G . M cke nna , I. S tr at fo rd G . 10: 00 M cK enn a ( U K ): M an ip u la tin g t h e tu m ou r m ic roe nv ir o n m ent in c om b ined m oda lity th er apy. 10: 25 T . P aune sk u (U S A ): N an o p ar tic le ta rg et in g and r ad io se n si ti zat ion . 10: 50 I . S tr at for d ( U K ): Ta rg et in g t u m ou r m eta b ol is m t o i m p ro ve th e ou tc om e o f ra di ot h erapy. 11: 15 A . C h al m er s ( U K ): C om b in in g P A R P in h ib it o rs w it h ra d iat io n t h erapy: ra ti on al e, str at eg y and po te nt ia l b io m ar ke rs .

S 1 4 . N o n -tar ge te d effe ct -its m ec h an is m and s igni fi canc e Ch ai r: M . K adh im , M . W at anab e 10. 00 M . K adhi m ( U K ): In tr od uct io n to n o n -ta rg et ed e ff ec ts . 10. 05: T . H ei ( U S A ): Is r ad ia ti on -i n d u ce d no n- ta rg et ed r es p ons e re le va nt t o hu m an he al th . 10. 30: M . W at an ab e (J ap an ): Th e or ig in o f ra d ia ti o n c ar ci n ogenes is is n ot D N A d am age. 10. 50: F . C uci n ot ta ( U S A ): M od u la r sy st em s b io lo gy and l o w do se r a d ia ti on re sp o n se s. 11. 10: M . L it tl e ( U S A ): C ircu la to ry d is ea se f ro m ex p os u re t o l o w -l ev el io n is ing r ad iat io n and es tim ate s o f p ot en ti al po pu la ti on r is ks : a m eta-a n al ys is of e p id em io lo gi ca l stu d ie s. 11. 30 S . S al om aa ( F in la n d ): H ighl ight s o f th e N O T E pr og ra m 2006 -2010.

S 1 5 . T h e use o f arch iv in g d at a an d b io log ic al m at erial – ex am p le s a n d s tr at eg ie s C h ai r: B . G ro sche, G. A . T h o m as 10: 00 P .N . S ch of iel d ( U K ): The ST O R E da ta wa re h ou se ; a n i n te rn ati o al i n frastruct u re f or d at a sh ar in g i n r adi o bi ol og y. 10: 30 W .F . M o rg an ( U S A ): M in ing t h e l if es p an stud ie s of b eagl es ex pos ed to ra d ia ti o n in u tero or as ju ve n il es. 10: 50 G .A. T h om as ( U K ): T h e C h erno by l Ti ssu e B an k – a m o d el fo r in te gr at in g “o m ics” re se arch o n si ng le b lo ck s o f ti ssu e. 1 1 :1 0 E . D oupl e ( Ja p an ): T h e us e o f u n iq ue arch iv ed d ata a n d b io lo gic al s am p le s by t h e Ra di at ion E ff ec ts R es earch F ou n d at io n . 11: 30 S . T ap io a n d O . A zi m zadeh ( G er m an y) : Q ual it at iv e and quant it ative pr ot eo m ic a n al ys is us in g fo rm al in -fixed pa ra ffi n -e m b ed d ed (F F P E ) tissu e.

S 16. Ind u ct io n of secondar y c an cers by i o ni zi n g r adi at io n C h ai r: I . T om a- D as u , D . A verbec k 10: 00 D . B re nner (U S A ): Un d er st an d in g a n d p o te n ti al ly r educi ng s ec on d can ce rs af te r ra d iot h era p y. 10: 25 Y . D ubr ov a ( U K ): T h e d el ay ed g en etic ef fe ct s of rad io th erap y – w h at w e know a n d w h at w e do n o t. 10: 50 J. H al l (F ra n ce) : R el at io n b et w ee n D N A re p air d ef ec ts and de ve lo p m en t of s ec ond ar y ca n cers . 11: 15 I . T o m a- D as u (S w ed en ): M od elli n g th e i n d u ct io n of s econdar y ca n ce rs f ro m ra di ot h erapy.

S 1 7 . M u lt ip le st ressors (c overs h u m an s an d en vi ron m en ta l st u d ie s) C h ai r: D . O u ght on, C. M ot h er si ll 10: 00 C. Se ym ou r ( C an ad a) : M u ltip le stre ssors – i ssu es t o p o n d er. 10: 20 P . E ri ks son (S w ede n ): D eve lo pm en ta l c o -e xp os u re to l ow d os es of i oni si n g ra d iati on an d e n viro nm en ta l to xi ca n ts d u ri ng a c ri ti ca l peri od o f brai n devel opm en t exac er bat e c og n it iv e d ef ec ts in a d u lt m ic e. 10: 50 M . M ai er ( G er m any) : P or ta bl e L ange nd or ff s ys te m fo r d et erm in at io n o f ef fe ct s of na no pa rt ic le s af te r ra d ia ti o n . 11: 10 I . G u se va C an u (F ra nc e) : E p id em io lo gy of u ra n iu m w o rk er s in F ra n ce . R ad io lo gic al and no t- ra d io log ic al ex p os u re a n d its e ff ec ts. 11: 30 B . S al b u ( N or w ay) : Subl et h al e ffe cts in j u ve n il e at la n ti c s al m on ( S al m o sa la r) i n d uced by m u ltip le stre ss or s (g am m a ra d ia ti on and me ta ls ).

S 18. R ad ia ti o n -p rodu in te rm ed ia te s – b asic p ro b le m s Ch ai r: I . Ca rm ic h ae l, S. P im b lo tt 10: 00 S . Pt as in sk a ( U D N A da m ag e i ndu ce fa st -f lo w in g m eta st ab sp ec ie s in a c ol d p la sm 10: 25 A . M cN am ar a (A u stral ia ): A c o m p ar of X -ray , p ro to n an d al beam t ra ck s tr u ct ur es M ont e C arl o s im u la ti 10: 50 R . E dge (U K ): R eacti on o f caro te n o w ith fre e ra d ica ls and s ing le t ox yg en . 11: 15 I . C ar m ic ha el ( S cavengers a s a m it iga strat egy a gai n st rad ia da m ag e i n m ac rom ol crys ta ll ograp h y.

St ar t tim e T u es day 30 A ugust 201 1 1 2 :0 0 C on feren ce l ec tu res C L 7 – C L 1 2 C L 7 . C h ai r: G . Ili ak is T . H al azone tis (S w itz er la n d): A T M -5 3 B P 1 pa th w ay in r es p o n se t o D N A d oubl e strand break s and c anc er de ve lo p m en t.

CL8 . Ch ai r: S. De m ar ia W. M cB ri d e ( U S A ): In fl am m at ory re sp on se s to r ad ia ti on .

CL9 . Ch ai r: A. W oj ci k E . C ard is (S p ain ): Mo b il e p h on es and h eal th r is ks .

C L 10. C h ai r: K . Sk ładow sk i B . van der K ogel (N et he rl ands ): H yp ox ia and i ts ro le i n radi ot h erapy of t u m ou rs .

C L 11. C h ai r: T . H ei A. K enn ed y (U SA) : A n ti ox id an ts: h el p o r h yp e.

C L 12. C h ai r: J . W Y . K ats u m u ra (Ja Ra d io ly si s o f su b and s u perc ri ti cal 1 3 :0 0 Lunc h br ea k ( C R 1 M ar m u ro w a a n d C R 2 K or cz ak ) 14: 00 P os te r s es si o n P O S 1 4 – P O S 2 2 ( P R 1 S tarzyń sk i an d P R 2 B ro n ie w sk i) P O S 1 4 D N A re p air ; P O S 1 5 G en etic in st ab ilit y; P O S 1 6 I n d iv id u al r ad ia ti on se n sitiv it y; P O S 1 7 R ad io ecol og y; PO S1 8 R adi at io n chem is tr y i n m at er ial s s ci en ce; P O S 1 9 R ad iat io n re se arch an d n u cl ea r p o w er; P O S 2 0 C o m b in at io n tre at m en ts; P O S 2 1 N o n -c an ce r e ff ec ts; P O S 2 2 H ea vy i o n s. A u th or s of o d d po st er n u m b er s ar e as ke d t o b e at t h ei r po st er s f ro m 14: 00 to 14: 45 A u th or s o f ev en p ost er n u m b er s ar e a sked t o be at t h ei r po st er s fr om 14: 45 t o 15: 30 15: 30 C of fe e b re ak ( C R 1 M ar m ur o w a an d CR 2 K or cz ak ) 16: 00 P le n ar y le ct u re P L 3 ( L R 1 K ongres ow a) Ch ai r: O . N iw a R . H ill (C an ad a) : T h e vari ed f aces of h yp ox ia i n ca n cer: f ro m radi at io n r esi st an ce t o m et as tas is t o s tem c el l n iche. I A R R H .S . K ap la n aw ar d l ect u re . 16: 45 D eb at e ( L R 1 K ongre so w a) C h ai r: J. W il li am s, I . T u re sso n D eb at e t itle : T h is h ou se b eli ev es t h a t f u rt h er a d va n ce s i n r ad iat ion on co lo gy w il l co m e f ro m p h ys ic s ra th er t h an f ro m r ad iat io n bi ol og y. De b at er s: B. M ac ie je w ski ( P ol an d) and S . B ent ze n ( U SA) 19: 30 Co nf eren ce ga la d in n er ( W arsaw Ce nt re E X P O X X I)

St ar t tim e W ednes day 31 A ugust 2 011 R O O M L R 1 K ongre so w a L R 2 R at u szow a L R 3 S k ło d o w sk a L R 4 W arszaw sk a L R 5 M ik oł aj sk a L R 6 K ru czk ow sk 08: 30 E ye o p en er l ec tu re s E O 13 – E O 17 E O 1 3 . C h ai r: R . W ak efor d K . K o d am a ( Jap an ): U p da te o n r adi at io n r is k es tim ate s fro m A -b om b su rv iv ors.

E O 1 4 . C h ai r: D .G . J o n es S . C h an dn a ( In d ia) : M ol ecu la r m echan is m s of e xtre m e ra d io re si stan ce d is p la ye d b y i n se ct c ells .

E O 1 5 . C h ai r: W . M cB rid e K . S kł adow sk i ( P ol and) : Com b in ed c h em o- ra di at io n th er apy.

EO 1 6 . C h ai r: D . Go od h ea d W . F ri edl an d (G er m any ): T ra ck struc ture si m u la ti on s fo r r ad ia tio n p h ys ic s, chem istry a n d b io lo gy .

E O 17 . C h ai r: J. M ichal J. F . W ishart ( U S A ): I li q u id r ad ia ti on chem and i ts app li cat io n s in n u cl ea r fu el tr ea tm 09: 30 C of fe e b re ak ( CR 1 M arm urow a and C R 2 K o rczak) 10: 00 S ym p os ia S 19 – S 2 4 S 1 9 . V as cu la r en d ot h el ia l ce ll res p on se t o rad ia ti o n - a ne w di m ens io n C h ai r: M . N at ara ja n, A. H ai m ov it z- F ri edm an 10: 00 M . N at ar aj an ( U S A ): Irra d iated en d ot h el iu m an d m echan ot ran sd u ct io n si gna ll ing . 10: 25 M . H au er -Je n se n (U S A ): V asc u la r-m ed iated n or m al ti ss u e i n ju ry - w h er e are w e an d w h er e are w e go in g? 10: 50 D .F . K u ci k ( U S A ): Adhe sive ness o f ao rt ic endo th el iu m i s in cr ea se d in re sp o n se t o h ig h L E T ra d ia ti o n . 11: 15 A . H ai m ovi tz- Fr ie d m an ( U S A ): T ar ge ti n g vascul ar e n d o th el iu m f or ra di os ens it iz at ion a n d tu m or c u re .

S 20. W h at , i f anyt hi n g have 'o m ics te chnol o gi es ta ught us a b ou t radi at io n ef fe ct s/ ri sks? Ch ai r: M . S ow a, A. L. B ro oks 1 0 :0 0 A .L B rooks (U S A ): In fl uenc e o f om ic s r es earc h on ra d ia ti o n p ara d ig m s and ri sk : past a n d f u tu re . 1 0 :2 5 S. Am u n ds on ( U SA) : In si gh t in to th e b ys ta n d er ef fe ct f rom f u nc ti ona l ge no m ics . 10: 50 P . St am b rook ( U S A ): W h at ‘O M IC S ’ ca n a n d ca nn ot t el l u s a b ou t D N A da m ag e r es p o n se a n d D N A re p ai r i n em br yoni c s tem ce lls ? 11: 15 M . So w a ( U S A ): W h at have ‘ om ics s tu d ie s ta ught us abou t h eal th ri sk s?

S 21. T h er agnost ic ra d iot h erapy C h ai r: K . S kł adow ski , R. S u w iń sk i 10: 00 R . Su w ińs ki ( P ol and) : T h e pers pect iv es o f TP M C C (T h erapeut ic P ers on al iz ed M u ltim o d al it y c an ce r C ar e) in c om b in ed tre at m en t fo r cancer of t he he ad a n d neck. 10: 20 R . T ar n aw sk i ( P ol and ): Feas ib ilit y and Sa fe ty of re d u ci ng t h e i rr ad iat io n d os e i n re gi on s o f a ctive neur o ge n es is f o r p ro p hy la ct ic cr an ia l irra d ia ti on i n p at ie n ts w it h s m al l- ce ll l u n g ca n cer. 10: 40 L . M is zcz yk ( P ol an d ): Ra d io th er ap y o f p ai n fu l vert eb ral he m an gi o m as . 11: 00 J. W yd m ań sk i (P ol an d ): Is the re a ro le fo r n eodj u va nt t h er ap y in g as tric c an ce r? 11: 20 K . Sk ładow sk i (P ol an d ): D o es a cce le rated rad io the rapy ref le ct ra d io b io lo gy : 15 ye ar ex p er ie n ce w it h C A IR (7 da ys i rr adi at ion) .

S 2 2. N anot ec hn o log y ta rg et in g D N A dama ge and repai r pat hways : adva n ce s f rom t h e clin ic Ch ai r: A. G eor ga ki la s, E. S . Y an g 10: 00 ( U S A ): Tar ge ti ng t h e ep id er m al grow th f ac tor re ce p to r (E G F R ) fa m il y to r en d er tu m or ce ll s su sc ep ti b le t o p ol y (A D P -R ib os e) p oly m era se (P ARP) i n h ib itio n . 10: 25 W .S . D yn an ( U S A ): R e- engi ne er in g t h e D N A doubl e s tr and br ea k m ach in er y f or th erape u ti c pu rp os es . 10: 50 O . M ar ti n ( A us tr al ia ): U se o f gam m a- H 2AX to m on it o r D N A da m ag e and r epai r in t ra n sl at io n al ca nc er r es ea rc h . 11: 15 K ar l T B u tt er w o rt h (U K ): A p p lic at io n o f g ol d n anop art icl es as r ad io se n sitis in g a ge n ts.

S 23. N ew d eve lo p m en ts in r ad ia tio n d osim etr y Ch ai r: S . Si m on , F. T ro m p ie r 10: 00 S . S im on ( U S A ): D os im etry t ec h n iq u es to sup p ort l o n g-t er m heal th r is k st ud ie s. 10: 25 P . K u ko ło w ic z (P ol an d ): D ev el op m en ts in d os im etry m eth o d s in ra d io th er ap y. 10: 50 J. B row n ( N or w ay) : D ev el op m en ts in d os im etry fo r expos u re s in t h e env ir onm en t. 11: 25: F . T ro m p ie r (F ra n ce) : D eve lo pm en ts and n ew tr ends f or r adi at io n a cc id ent d os im etry w ith b io lo gic al sa m p le s and pers on al i te m s.

S 24. R ad ia ti o n c h em in m at eri al s scien ce Ch ai r: J . Be ll on i, S . T 10: 00 M . W as h io ( Ja p N an o -/ m ic ro-fab ri ca ti of p ol ym er ic m at er ia u si n g f ocuse d i o n be am 1 0 :3 0 M . M os tafa vi (F ra n ce ): N ew stra te gy to fo rm b y ra d io ly ti c m et h o d n anopar ti cl es m et al and s em ic o nduct 11: 00 T . K oza w a ( Ja p R eacti on o f th er m al ize el ec tr on s i n r es is t m at 12: 00 P le n ar y le ct u re P L 4 ( L R 1 K ongres ow a) Ch ai r: P. O’ N ei ll D. B re n n er ( U S A ): E xp lori n g t h e tw o tw o- ed ge d sw ord s. R R S G . F ai ll a aw ard l ec tu re. 1 3 :0 0 Lunc h br ea k (C R 1 M ar m u row a a nd CR 2 K orc za k)

St ar t tim e W ednes day 31 A ugust 2 011 14: 00 P os te r s es si o n P O S 2 3 – P O S 2 9 ( P R 1 S ta rz yń ski a n d P R 2 B roni ew sk i) P O S 2 3 R ad ia ti o n p ro te ct ion ; O S 24 L o w do se e ff ect s; P O S 25 S te m c el ls ; P O S 26 R ad iat io n d am age t o b io m ol ecul es ; P O S 2 7 N orm al t is su e da m ag e; P O S2 8 M ic rodos im et P O S29 Phys ic al d os im et ry . A u th or s of o d d po st er n u m b er s ar e as ke d to b e at t h ei r po st er s f ro m 14: 00 to 14: 45 A u th or s o f ev en p ost er n u m b er s ar e a sked t o b e a t t h ei r p ost er s fr om 1 4 :4 5 t o 1 5 :3 0 15: 30 C of fe e b re ak ( C R 1 M ar m u ro w a a n d CR 2 K orc za k) 16: 00 P le n ar y le ct u re P L 5 ( L R 1 K ongres ow a) C h ai r: K . W il li am s D . H ir st ( U K ): N an o p ar ti cl e th er ap y w ith t h e M id as t ou ch. A R R W ei ss aw ard l ec ture. 16: 45 P le n ar y le ct u re P L 6 ( L R 1 K ongres ow a) Ch ai r: A: W oj ci k P . J eg go ( U K ): R ev ea li n g t h e c om p le xi ty of D N A d oubl e stra n d b re ak r epai r; t h e p ro ces se s, t h e l es io n a nd t h e en vi ro n m en t. ER R S B ac q a n d Al ex an d er a w ar d l ec tu re . 17: 30 S ym p os ia S 25 – S 2 9 S 25. C el l ad h es ion / mi gr at io n i n r es p on se to ir ra d ia tio n Ch ai r: M .H . B arcel lo s- H o ff , N . C orde s 1 7 :3 0 M . P ruschy (S w it ze rla n d ): T ar ge ti n g th e i rra d ia ti o n -in d u ce d pr oa n gi og eni c and p ro -i n vasi ve p h en o ty p e. 1 8 :0 0 M .H . B arce llo s- H o ff (U S A ): M ec h an is m s an d cons equ enc es o f r adi at io n - in d u ce d phen ot ype s. 18: 30 N . Cordes ( G er m an y) : Shou ld I s ta y or s houl d I go ? C el l m igrat io n af te r irra d ia ti on.

S 2 6 . R ad ia ti o n researc h aw ar d sessi on Ch ai r: P. O’ N ei ll 17: 30 M . B oerm a ( U S A ): Ex p er ime n ta l r ad ia ti on - nduc ed h ea rt di se as e: pa st , pr es en ce a n d f u tu re . 18: 00 A. Paun (C an ad a) : G en etic vari at io n in im m u n it y al te rs mu ri n e re sp o n se t o w h ol e t h or ax irra d ia ti on.

S 27. T u m or h yp ox ia and r adi ores is ta n ce C h ai r: B . W out er s, H. Ha ra d a 17: 30 H. H ar ad a ( Ja p an ): M ole cu la r m echan is m behi nd H IF -1-m ed ia te d ra di or es is ta nc e an d p ostir ra d ia tio n re curr en ce of t u m ors. 18: 00 B ra d W ou te rs (C anada) : N ov el o xyge n sens it iv e si gn al li n g p athw ay s and t h ei r po te n ti al as t h erapeut ic t ar get s. 18: 30 R . A li ( U S A ): Im ag in g of hy p ox ia -i n du ce d ra d ia ti o n re si st an ce and t re at m en t re sp on se.

S 28. C om p ut at ional approac h t o u n d er st and in g D N A prot ec ti on by prot ei n b indi ng Ch ai r: M. Da vi d ko va , R. M ar ti n 17: 30 M . D avi d ko va ( C ze ch R ep u b lic ): E ff ec t o f p ro te in bi n d in g t o di re ct an d in d ir ect r ad ia ti on da m ag e to D N A . 17: 50 S . Pt as in sk a (U S A ): T h e a cti on o f am ino aci d s on e le ct ron i rradi at ed D N A fi lm s. 18: 10 R . M ar ti n ( A us tr al ia ): The d ev el o pm ent of n ew ra d iop ro te ct ors – D N A b in d in g stud ie s w it h m et h yl proa m in e an al o gues . 18: 30 H . F u ji m ot o ( Jap an ): S truct ural a n al ys is o f th e i n te ract io n be tw ee n th e K u p ro te in a n d D N A .

S 29. R ad ia ti o n c h em ic st u d ie s o f b io ac tiv e co m p ound s Ch ai r: J .L . G ęb ic ki , T. M u khe rj ee 17: 30 T . M u kh er je e (In M echan is tic st u d ie s on h er b al d rug s an d th act iv e i n gr ed ie n ts i n re to t hei r a n ti ox id ant a n ra d io p ro te ct io n a b ilit 18: 00 M . L an d au er ( U R ad iop ro te ct io n by th e s o y i sof la vo ne g en 18: 30 A . S ik or a ( P ol an No ve l t o ol s i n t h e r es earc on a n ti ox id an ts - t h e gl p ro filin g o f R O S /R N S in ce ll -f re e an d ce llu la sy st em s.

St ar t tim e T h urs d ay 1 S ep te m b er 2011 R O O M L R 1 K ongre so w a L R 2 R at u szow a L R 3 S k ło d o w sk a L R 4 W arszaw sk a L R 5 M ik oł aj sk a L R 6 K ru czk ow sk 08: 30 E ye o p en er l ec tu re s E O 18 – E O 23 E O 1 8 . C h ai r: P . J eg go W . B on n er ( U S A ): The in s and ou ts o f D N A D S B re p air f oc i.

E O 1 9 . C h ai r: E . A zz am B. M ar pl es ( USA) : C el l d ea th p at h w ay s: m echan is m s a n d re le va n ce to th e ra d ia ti on re sp o n se .

EO 2 0 . C h ai r: D. Br en n er G . T aucher -S ch ol z (G er m an y): R ad ia ti on and D N A le si on s: w h en q u ality m at te rs .

E O 2 1 . C h ai r: J . H endr y P .- K . Z hou (C h in a) : H eal th ef fe ct s o f e xpo sure to ra di at io n f rom r es id en ti al rad io act iv e b u il di ng ma te ri al s.

E O 2 2 . C h ai r: P . W ard m an R. A n d er so n ( N ew Z ea la n d ): O p tim is in g d ru gs th at ta rg et r edox pa th w ays .

E O 23 . C h ai r: J. W il li V . M ei neke ( G er m any P lanni n g/ res p o nd in g to n u cl ea r te rrori sm . 09: 30 C of fe e b re ak ( C R 1 M ar m ur o w a an d CR 2 K or cz ak ) 10: 00 S ym p os ia S 30 – S 3 5 S 3 0 . B io lo gica l effe ct s of l ow dos es Ch ai r: S . Sa lo m aa , D . A verbe ck 10: 00 S. Sal om aa ( F in la nd ): Bi ol o gic al e ffe cts at l o w d ose s - E u ro p ea n L o w D ose R isk R es ea rch S tr at egy 10: 15 C . B ad ie ( U K ): W h at do w e k n o w ab ou t th e m echan is m s o f c an ce r in d u ct io n a n d h ow m ig h t th is a ff ec t t h e sh ap e o f t h e dos e- res p ons e at l o w d os es . 10: 30 R . W akef or d ( U K ): T h e r isk o f c an ce r fr om lo w le ve l e xp os u re to r ad ia tio n – t h e ep id em io lo gi ca l ev id en ce . 10: 45 M . A tk in son (G er m an y): W h at d o we know a b ou t t h e f a ct o rs underl yi ng i n d ivi d u al su sc ep ti b iliti es a n d h o w la rge i s t h is vari at io n ? 11: 00 E . Cardi s ( S pai n ): M ole cu la r e p id em io lo gy and l o w do se ri sk . 11: 15 J. -R . Jo ur d ai n (F ra n ce ): W h at do w e k now abou t t h e m echan is m s of no n- cancer ef fe ct s at lo w and m o de ra te d os es ? 11: 30 K . O zas a ( Ja p an ): R ad ia ti on r isk of c anc er and no n can ce r m o rt al it y in a to m ic b om b s urvi vors , 1950- 2003.

S 31. D ynam ic s of r ep ai r of r ad ia ti on- in du ce d ce llu la r D N A d am ag e in r ea l tim e Ch ai r: D . Ch en , A. Ya su i 10: 00 A. Ya su i ( Ja p an ): R ep ai r m echa ni sm s o f D N A stran d b reaks i d en tifi ed by v is u al iz in g p ro te in s in h u m an ce lls . 10: 25 B. J ak o b ( G er m an y) : S tudy of e arl y D N A d am age re sp on se s after ch ar ge d p art ic le i rra d iat io n by be am li n e m icr os co py . 10: 50 J. At en ( N et he rl ands ): Mo ve m en t o f D N A doubl e-stran d b re aks . 11: 15 A . A sai th am b y ( U SA ): V is u al iz at io n o f sp ati o- te m p or al d yn am ic s of i o n iz ing radi at io n in d u ce d cl us te re d D N A le si o n s.

S 32. N ew t ool s in b io lo gi ca l dosi m et ry Ch ai r: P . V oi si n , B. T h ie ren s 10: 00 B . T h ie re ns ( B el gi u m ): T h e a u to m ate d m ic ro n u cl eu s assa y as a r el ia b le bi o d os im et ri c t ool f o r po pu la ti on tr ia ge i n larg e sc al e r ad iat io n acci d en ts . 10: 20 A. J aw or sk a ( N or w ay ): MU L T IB IO DOS E : m u lti- di sc ip li na ry bi o d os im et ri c t ool s to ma n ag e h ig h s cal e ra d io log ic al c as u altie s. 1 0 :4 0 M . G m ar ( F ranc e) : BOO S T E R : B iO- d OS im et ri c T o ol s f or tr ia gE to R es p onders. 11: 00 G . G ruel ( F ra n ce ): To w ar d s t h e v al ida ti on o f ge ne e xp re ss ion m o di fi ca ti ons as a b iodo si m et er. 1 1 :2 0 : P . V oisin ( F ran ce ): S tanda rd is at io n of bi ol ogi ca l d os im et ry b y cy to ge n eti cs : s ta tu s, advan ta ges and l im it at io n s.

S3 3 . C ount er m eas ur es in c ase o f a cci d en ta l rad ia ti on e xposure C h ai r: V . M ei neke , J. W illi am s 10: 00 J. W illi am s (U S A ): A n im al M o d els fo r co un te rm ea sure re search. 10: 25 M . D rouet ( G ra nc e) : Me se n ch ym al s te m c ell th er apy fo r t rea tm ent o f lo ca li ze d r adi at io n i n ju ri es (t he m in ip ig m o d el ). 10: 50 X Z R an X Z (C h in a): St u d ie s on he m ato p oie ti c pr ot ec ti on a n d i m m u ni ty ad ju st m en t i n co m b in ed ra d ia ti o n -t h er m al in ju ry . 11: 15 M . H au er -Je n sen (U S A ): T h e s o m at os ta ti n anal og , SO M 230, is a hi ghl y ef fe ct iv e m itig ato r o f in te st ina l ra d ia tio n in ju ry .

S 34. S te m c el ls a n d reg en er at ive m ed ic in e f o r th e tr ea tm en t of ra d io th era p y s id e e ffe ct s C h ai r: M . B en d er itte r, C. L im ol i 10. 00: P V an L u ij k (N et he rl and) : S tem c el l sp ar in g ra d io the rapy: a no ve l a p proach t o th e p rev en ti on o f ra d iat io n- in d u ce d x er os to m ia . 10. 15: C L im ol i (U S A ): Cog n it iv e r es tor at io n a ft er cy to to xi c ca n ce r tre at m en ts. 10. 30: C G uha ( U SA ): H ep ato cy te t ra ns pl an ta ti on fo r a m el io ra ti o n o f R IL D . 10. 45: A C h ap el ( F ra n ce ): Me se n ch ym al s te m c el l am el io ra te s se ve re ra d ia ti on pe lv ic c om p li ca ti on: cl in ic al tra n sf er . 11. 00: O M al ar d ( F ra n ce) : B one r eg ene rat ion a n d engi neer in g i n i rr ad ia te d fi el d s. 11. 15: R T am ar at ( F ra n ce) : R ege nera tive m ed ic in e b as ed o n s te m c el l i n je ctio n fo r ra d ia ti o n b u rn tr ea tm en t. 11. 30: M K li n ge r ( It al y) : F at graf ti ng a ft er ma st ec to my and ra d io th erapy .

S 3 5 . R ad ia ti o n researc and nuc lear p o w er Ch ai r: D . S w ia tl a- W oj A. Ch m ie le w sk i 10: 00 B . M in cher ( U Ra d ia ti on chem is tr y e on nu cl ea r s ol ve n t ex tra ct ion: e xa m pl es CM P O ra d io ly sis . 10: 25 A . C hm ie le w ski (P ol an d ): C h em is tr y f nu cl ea r en er gy o f t h e f 10: 50 J. W ren (C an ad R adi at io n -i n du ce d a q chem istry a n d corr os in n u cl ear r eact or env ir onm en ts . 11: 15 D . Sw ia tl a- W oj (P ol an d ): M od elli ng a si m u la ti o n f or c ont ro chem istry i n a d va n ce nuc lear e n er gy s ys te ms

St ar t tim e T h urs d ay 1 S ep te m b er 2011 1 2 :0 0 C on feren ce l ec tu res C L 1 3 – C L 1 8 C L 13. C h ai r: H . P ar et zk e M .H . B ar ce llo s- H of f (U S A ): S ys te m s bi ol ogy – w h er e ar e we a n d wh er e c an we g o?

C L 14. C h ai r: E . B lak el y M . D uran te ( G er m any) : Pa rt ic le t h er ap y: f ro m th e l ab o ra to ry t o th e c lin ic .

C L 15. C h ai r: M . M os taf avi P. U la ń sk i ( P ol an d ): R ad iat io n chem is tr y and te ch nol og y o f pol ym er s: re ce nt a d va n ce s.

C L 16. C h ai r: Y . D u br ov a C. W es t ( U K ): G eno m ic s and t h e th er apeut ic re sp o n se .

C L 17. C h ai r: C . B ad ie J. -L . R av an at ( F ranc e) : R adi at io n -i n du ce d D N A dam ag e i n m am m al ia n ce lls – n ov el t yp es o f l esi on s.

C L 18. C h ai r: B . M M . J o ns son (S w R adi at io n -i n du ce d isso lu ti on o f sp n u cl ea r fue l. 1 3 :0 0 Lunc h br ea k ( C R 1 M ar m u ro w a a n d C R 2 K or cz ak ) 14: 00 P len ar y le ct u re P L 7 ( L R 1 K ongres ow a) C h ai r: A . Cebul ska -W as il ew sk a H . La n ge vi n -J ol io t ( F ra nc e) : M ar ia Sk ło d ow ska -C u ri e 15: 00 C of fe e b re ak ( C R 1 M ar m ur o w a and C R 2 K or cza k ) 15: 30 P os te r s es si o n P O S 3 0 – P O S 4 1 ( P R 1 S tarzyń sk i an d P R 2 B ro n ie w sk i) P O S3 0 Sy st em s b iol og y; P O S3 1 M o du la ti on o f r ad iat io n dam ag e; PO S 32 N on ion iz in g ra d iat io n ; PO S 33 N o n -t ar get ed e ff ect s o f ra d iat io n ; P O S 34 P ro teom ic s; P O S 3 5 R ad ia ti o n c ar ci n ogenes is ; PO S 36Tum ou r b io lo gy; PO S 37 R ad iat io n chem is tr y: b as ic p ro b le m s; P O S 3 8 R ad ia ti on t echno lo gi es ; P O S 3 9 R ad io th er ap y ef fe cts; P O S 4 0 R ad ia ti o n b io p h ys ics ; P O S 41 Trac k s truct ure. Au th or s o f od d p os te r num b er s ar e as ke d t o be a t th ei r p osters fr om 1 5 :3 0 t o 1 6 :1 5 Au th or s o f ev en p ost er n u m b er s ar e a sked t o b e a t t h ei r p ost er s fr om 1 6 :1 5 t o 17: 00 17: 00 C los in g cere m on y (L R 1 K ongresow a) Ch ai r: M .K. J ani ak Cl os in g w or d s: O h ts ur a N iw a – Pr es id en t o f I A R R and A n to n in a Cebul sk a- W as il ew sk a – P res id ent o f IC R R 2011 In vi ta ti on t o IC R R 2015 in K yot o, Ja p an : M as ah ir o H iraok a - P re si d en t of t h e I C R R 2015