Örebro Studies in Medicine 122 I
ÖREBRO 2015 2015JA
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jasmine evert was born on September 26th 1982. In
2009 she received her Masters degree in Medical Biosciences from Linköping University, and registered as a PhD student in September 2009. During this research period she has been active at the Systems Biology Research Centre at the University of Skövde as responsible for seminars and work-shops within the research centre. Jasmine has also been teaching biomedical students at the University of Skövde and medical students at Örebro University.
Colorectal cancer is a common malignancy with more than 6000 new cases diagnosed each year in Sweden. The mortality rate is approximately 50%, making it a common cause of cancer-related death. The primary treatment is surgery, which is often combined with radiotherapy or chemotherapy in order to decrease the risk of recurrence and increase survival. Both radio-therapy and chemoradio-therapy are associated with side effects and there is sig-nificant variation in treatment response even among patients at the same tumour stage. Approaches are being made to improve prognostic methods, including analysing molecular and genetic markers. Although these markers are promising they are not yet routinely used. The aim of this thesis was to study factors influencing the response to radiotherapy and chemotherapy by analysing surgical material from colorectal cancer patients and colon cancer cell lines in vitro.
issn 1652-4063 isbn 978-91-7529-070-6
