Microbial regulation of Insulin-like peptide 5 and its implication on metabolism and bariatric surgery

There have been few studies on the binding sites of IGF-II to the respective recep- tors, but the existing investigations based on mutations of IGF-II and its ability to bind

Because both enzymes are found in higher levels in several cancer cell types, it was investigated which role these structures have in cancer cells and if they

The results from the transcriptional analyses showed a clear synchronized in- crease of transcripts during nitrogen depletion of the genes encoding the large subunit of the

Sixty (30 men and 30 women) consecutively recruited Caucasian patients and 20 matched healthy controls (10 men and 10 women) were studied in Papers IV and V. The patients had

The overall aim of this thesis was to determine whether the insulin/IGF-I system is of importance for outcome of ischemic stroke (IS) also in humans and whether insulin

Thus, in this thesis, we also investigated whether INSL5 and the gut microbiota directly contributes to the metabolic improvements following the bariatric procedure called

Our previous studies have shown that one differentially regulated gene in skeletal muscle comparing AMPKγ3 knockout mice to wild-type littermates is Stk25, which raised

AMP-activated protein kinase (AMPK), a central regulator of energy homeostasis, increases insulin sensitivity in liver and skeletal muscle and lowers the plasma