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issn 1652-4063

isbn 978-91-7668-855-7 Örebro Studies in Medicine 66örebro 2012

Doctoral Dissertation

Local Infiltration Analgesia in Knee Arthroplasty

Per Essving

Medical Science with focus on Surgery

Per Essving (1960) received his medical degree in 1987 at Uppsala University. After completing his train-ing in orthopedic surgery in 1994, he has worked at the Department of Orthopedic Surgery at Örebro Univer-sity Hospital. He was registered as a PhD student at Örebro University in 2006 and professor Kjell Axelsson has been his research supervisor.

The acute pain following knee arthroplasty surgery is often severe. A new technique for postoperative pain management, local infiltration analgesia (LIA), has recently been developed. LIA involves a long-acting local anesthetic (ropivacaine), a non-steroid anti-inflammatory drug (ketorolac) and epinephrine infiltrated into the knee joint during surgery and injected postoperatively via a catheter. This thesis presents four studies investigating the role of LIA following knee arthroplasty.

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Local Infiltration

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