Bioinformatics Programme
Uppsala University School of Engineering
UPTEC X 06 033 Date of issue 2006-08 Author
Eva Schreil
Title (English)
Evaluation of Pattern Recognition Methods Applied to In Vitro IgE Measurements
Title (Swedish) Abstract
Food allergens from the plant kingdom are an important source of allergic reactions which are difficult to diagnose. Methods that can visualise relationships between these allergens are therefore needed. The main aim of this project was to evaluate pattern recognition methods for visualisation of multidimensional measurements of immunoglobulin E (IgE) in blood sera.
Multidimensional scaling (MDS), a method for visualisation of multidimensional data in a reduced space, was evaluated and tested on IgE data from three patient groups with different IgE reactivity to cereals and grass in order to reveal relationships between food allergens from the plant kingdom. The results show that MDS is a useful and robust method for visualisation of IgE data.
Keywords
allergy, IgE, pattern recognition, multidimensional scaling Supervisors
Annica Önell Ingvar Edlert Phadia AB, Uppsala
Scientific reviewer
Mats Gustafsson
Department of Engineering Sciences, Uppsala University
Project name Sponsors
Language
English
Security
Secret until 2007-08-31
ISSN 1401-2138 Classification
Supplementary bibliographical information Pages
58
Biology Education Centre Biomedical Center Husargatan 3 Uppsala Box 592 S-75124 Uppsala Tel +46 (0)18 4710000 Fax +46 (0)18 555217
