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Data are mean±SEM*, mean±SD° or median (range)#. CABG§: Coronary artery bypass grafting.

LVEF†: left ventricular ejection fraction. CPB‡:Cardiopulmonary bypass.

Table 1

Demographic data, paper I, II, III and IV

I isoflurane (n = 16)

II

sevoflurane (n = 18)

III TAVI(n = 21)

IV SAVR(n = 10)

Age (yr) 71±2.6 * 72±1.9 * 81±6 ° 73±6 *

Sex Male

Female 14

2 13

5 11

10 8

2 Body Surface area (m2) 1.89±0.0 * 1.89±0.04 *

Body Mass Index 24±2.7 ° 30±3 *

Logistic Euroscore, % 19.2±8 °

NYHA class I / II / III / IV 0/0/16/5 4/2/3/1

Aortic stenosis gradient,

mmHg 56±19 °

(mean) 92±14*

(max.) NT-pro-BNP level, ng/L 5070

(291- 35000)#

Creatinine, µmol/L 106±38 ° 88±11 * Co-Morbidities

Hypertension Diabetes

Previous stroke or TIA Atrial fibrillation

Previous cardiac surgery

3 11 9

52 310

35 11 0 Procedure

CABG§

Valve Combined Maze

Ascending aortic aneurysm

43 81 0

14 110 2

10

LVEF† (%) 54±3.3 * 55±2 * 52±13 ° 59±9 *

CPB‡ time (min) 128±9.5 * 109±6 * 93 ± 25 *

Cross-clamp time (min) 84±8.6 * 81±5 * 74 ± 24 *

(22)

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References

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