Increasing the interpretability of Alzheimer-related biomarkers:

Skillbäck T, Mattsson N, Hansson K, Mirgorodskaya E, Dahlén R, van der Flier W, Scheltens P, Duits F, Hansson O, Teunissen C, Blennow K, Zetter- berg H and Gobom J.. A

Abbreviations Aβ, β amyloid AD, Alzheimer’s disease ADAM, A Disintegrin And Metalloproteinase APOE, Apolipoprotein E APP, amyloid precursor protein AUROC, area under the

In this thesis, we have examined the expression and secretion of several AD- associated proteins during hiPSC differentiation to cortical neurons, including APP and its

The cross-sectional part included an HIV-positive group (n = 252) divided into six subgroups: Four groups of neuroasymptomatic (NA) patients without treatment,

This thesis evaluates biomarkers related to: neuronal injury (neurofilament light chain protein (NFL) and total tau (t-tau)); immune activation (neopterin); and altered

Blood oxygen level-dependent (BOLD) fMRI was used to assess healthy volunteers, and in line with the results from the PET study, 9-repeat carriers displayed higher reactivity of

By using the taxonomy by Kelly and colleagues (2013; 2015; 2016), the interrogations could be studied in a holistic manner, examining interactions between different

The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer's disease.. INSTITUTIONEN FÖR NEUROVETENSKAP