Molecular Biotechnology Program Uppsala University School of Engineering

The expansion of the voltage-gated calcium channel alpha 1 subunit families (CACNA1) of L and N types was investigated by combining phylogenetic analyses (neighbour-joining and

In this degree project Sortase A from Staphylococcus aureus was explored and potential inhibitors were investigated by performing enzyme activity and bacterial binding assays. A

The characterized genes showed gradual improvement and divergence of functions, supporting the Innovation-Amplification-Divergence model of

Moreover, by applying a molecular clock, it is proposed that the Domestic cat lineage has experienced several expansions representing domestication and/or breeding

It showed large dynamic range, no measureable non-specific binding and high sensitivity (with linear range around 0.1 – 10 µg/ml depending on the proteins). The method

This combined with recent research showing biocompatibility with cells gives the spider silk a wider range of applications such as for biomedical applications. pastoris, with each

Escherichia coli, 23S rRNA, Post-transcriptional modification, In vitro, Peptidyl transferase centre, domain V, Methylation, Pseudouridine, Reverse

The fibrinolytic enzyme tissue type plasminogen activator (t-PA) is released by the vascular endothelium to limit the growth of blood clots and ultimately prevent the occurrence of