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Molecular Biotechnology Programme Uppsala University School of Engineering UPTEC X 01 026

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Molecular Biotechnology Programme Uppsala University School of Engineering UPTEC X 01 026

Date of issue 2001-05

Author

Lovisa Forssell

Title (English)

Curved micromachined surfaces in polymeric material for cell culturing

Title (Swedish) Abstract

Earlier work has shown that human cells react to very small structures with sharp edges. In this Degree project, a method for production of well-defined curved micromachined structures in polycaprolactone (PCL) was developed. Human fibroblasts were cultured on these structures and fluorescence stained for actin. Cells were found to align to and stretch along the grooves.

Keywords

Micromachining, quartz, polycaprolactone, cytoskeleton, fibroblasts, fluorescence Supervisors

Fredrik Nikolajeff

Materials Science Division, Uppsala University Examiner

Karin Caldwell

Center for Surface Biotechnology, Uppsala University

Project name Sponsors

Language

English

Security

ISSN 1401-2138 Classification

Supplementary bibliographical information Pages

18

Biology Education Centre Biomedical Center Husargatan 3 Uppsala Box 592 S-75124 Uppsala Tel +46 (0)18 4710000 Fax +46 (0)18 555217

References

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