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Molecular Biotechnology Programme Uppsala University School of Engineering UPTEC X 01 012

Date of issue 2001-02

Author

Frida Jernström

Title (English)

Self-assembled monolayers of alkanethiols: A study of surface composition, wettability, and adsorption of proteins and peptides

Title (Swedish) Abstract

Self-assembled monolayers (SAMs) of alkanethiols on gold were produced and characterised using contact angle goniometry, ESCA, SPR, and MALDI-MS. Two-component SAMs of polar and non-polar alkanethiols were included in the study. An alkanethiol equipped with an aromatic tail group was synthesised, and surface synthesis was carried out on hydroxyl- presenting SAMs to introduce fluorinated and aromatic tail groups respectively.

Keywords

Self-assembled monolayer, alkanethiols, surface synthesis, protein adsorption, peptide adsorption, SPR, MALDI-MS

Supervisors

Helene Dérand, Gyros AB

Examiner

James Van Alstine, KTH

Project name Sponsors

Language

English

Security

ISSN 1401-2138 Classification

Supplementary bibliographical information Pages

36

Biology Education Centre Biomedical Center Husargatan 3 Uppsala Box 592 S-75124 Uppsala Tel +46 (0)18 4710000 Fax +46 (0)18 555217

References

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