Linköping University Medical Dissertations No. 1583
Inflammation and tendon healing
Parmis Blomgran
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FACULTY OF MEDICINE AND HEALTH SCIENCES
Department of Clinical and Experimental Medicine Linköping University
SE-581 83 Linköping, Sweden
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Question
Methods
Answer
I Do different degree of mechanical loading influence the immune cell composition?
Yes
II Does a COX-2 inhibitor influence
the immune cell composition? No
III Can corticosteroids be beneficial for tendon healing? When?
Yes
After the inflammatory phase
IV Does a COX-2 inhibitor interfere with stimulatory effect of mechanical loading during early tendon healing? Via mechanotransduction or microdamage? Yes Microdamage