Symposium
Epigenetic regulation in
myeloid and lymphoid
malignancies
13 October, 2014
The Svedberg Lecture Hall (B8)
BMC, Husargatan 3
Uppsala, Sweden
Program at a glance
09:00 – 09:30 Registration and Coffee
09:30 – 09:40 Welcome note
Session 1.
Chair: Sören Lehmann
09:40 – 10:30 BLUEPRINT to decode the epigenetic signature written in blood Hendrik Stunnenberg,Radboud University, Netherlands
10:30 – 11:10 Chromatin remodelling in
normal myelopoiesis
Karl Ekwall, KI, Stockholm, Sweden
11:10 – 11:50 Origins of aberrant DNA methylation in acute myeloid leukemia Carsten Müller-‐Tidow, University of Muenster, Germany
11:50 – 12:30 Unraveling the epigenome of acute myeloid leukemia in clinical practice Sören Lehmann, KI, Stockholm, Sweden
12:30– 13:40 Lunch
Session 2.
Chair: Richard Rosenquist
13:40 -‐14.20 Epigenetics in CLL
Christoph Plass, German Cancer Research Center (DKFZ), Germany
14.20 -‐15.00 Epigenetics in ALL Jessica Nordlund, SciLifeLab, Uppsala
Session 3.
Chair: Helena Jernberg-‐Wiklund
15:15 – 16:15 Keynote Speaker:
Epigenetic basis and targeted therapy of B-‐ cell lymphomas
Ari Melnick, Weill Cornell Medical College New York, NY
16:15 – 16:40 Coffee Break
16:40 – 17:20 Displacement of BRD3/4 from chromatin as an effective treatment for MLL-fusion leukaemia
Brian Huntly, University of Cambridge; Cambridge Cancer Centre
17:20 – 17:30 Concluding remarks
Application Deadline: October 1, 2014
For registration, updated information about the event, including practical information please visit: http://www.scilifelab.se/events/ The symposium is free of charge (on a first come basis).
Scientific Committee:
Helena Jernberg-‐Wiklund, Jessica Nordlund Richard Rosenquist, Sören Lehmann
Figure reprinted by permission from MacMillan Publishers Ltd: Nature 454, 711-‐715 (2008).
